Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | EP300 | Q09472 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.35 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | P2RY10 | O00398 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PRKCA | P17252 | 1/20 | 0.31 |
| ▸ | CD81 | P60033 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8928144 | 1.00 | ALDH1A1 (0.39) | ALDH1A1EP300EPHX2TBXAS1CES2 | |
| SCHEMBL22972968 | 0.90 | ALDH1A1 (0.48) | ALDH1A1EP300TBXAS1CD81 | |
| SCHEMBL523128 | 0.88 | ALDH1A1 (0.45) | ALDH1A1EP300TBXAS1KMT2ACD81 | |
| SCHEMBL9487570 | 0.88 | ALDH1A1 (0.45) | ALDH1A1EP300TBXAS1KMT2ACD81 | |
| SCHEMBL15475663 | 0.86 | ALDH1A1 (0.37) | ALDH1A1EP300TBXAS1CD81 | |
| SCHEMBL15475483 | 0.86 | ALDH1A1 (0.37) | ALDH1A1EP300TBXAS1CD81 | |
| SCHEMBL33441 | 0.86 | CD81 (0.34) | ALDH1A1CD81CA2 | |
| SCHEMBL21082716 | 0.86 | CD81 (0.34) | ALDH1A1CD81CA2 | |
| SCHEMBL15475742 | 0.86 | CD81 (0.34) | ALDH1A1CD81CA2 | |
| SCHEMBL3081155 | 0.86 | CD81 (0.34) | ALDH1A1CD81CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0591204-B1 | PHARMACEUTICAL FORMULATIONS | BAUER KURT H (DE) | 1997-01-08 | — | — | EP | disclosed |