SCHEMBL8928183

SCHEMBL8928183

CC=COc1ccccc1CCCCCCC

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRA P10827 1/20 0.54
THRB P10828 1/20 0.54
LIPG Q9Y5X9 1/20 0.47
ALOX5 P09917 1/20 0.46
PTGS2 P35354 1/20 0.46
PPARA Q07869 3/20 0.44
PPARG P37231 2/20 0.43
NR1H2 P55055 1/20 0.40
NR1H3 Q13133 1/20 0.40
BCHE P06276 1/20 0.38
BID P55957 3/20 0.38
MCL1 Q07820 3/20 0.38
BCL2L1 Q07817 2/20 0.38
BAK1 Q16611 2/20 0.38
KAT8 Q9H7Z6 2/20 0.38
EP300 Q09472 1/20 0.38
KAT2A Q92830 1/20 0.38
KAT2B Q92831 1/20 0.38
KAT5 Q92993 1/20 0.38
SAE1 Q9UBE0 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acrylic Acid SCHEMBL27603281 0.88 THRA (0.63) THRATHRBLIPGALOX5PTGS2
SCHEMBL64326 0.87 THRA (0.56) THRATHRBLIPGALOX5PTGS2
SCHEMBL11129111 0.87 THRA (0.56) THRATHRBLIPGALOX5PTGS2
SCHEMBL11323416 0.87 THRA (0.56) THRATHRBLIPGALOX5PTGS2
SCHEMBL5491774 0.87 THRA (0.56) THRATHRBLIPGALOX5PTGS2
SCHEMBL18139176 0.87 THRA (0.56) THRATHRBLIPGALOX5PTGS2
SCHEMBL27998535 0.83 THRA (0.50) THRATHRBLIPGALOX5PTGS2
SCHEMBL6898393 0.82 THRA (0.55) THRATHRBLIPGALOX5PTGS2
SCHEMBL8179968 0.82 THRA (0.58) THRATHRBLIPGALOX5PTGS2
SCHEMBL28424848 0.82 THRA (0.62) THRATHRBLIPGALOX5PTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5696064-A FROM CARBON MONOXIDE AND A NUCLEOPHILIC TRAPPING AGENT EXXON CHEMICAL PATENTS INC. (US) 1997-12-09 US disclosed
US-5629434-A REACTION PRODUCT OF POLYMER WITH AT LEAST ONE ETHYLENIC DOUBLE BOND WITH CARBON MONOXIDE AND NUCLEOPHILIC TRAPPING AGENT; DISPERSANTS, VISCOSITY MODIFIERS EXXON CHEMICAL PATENTS INC (US) 1997-05-13 US disclosed
EP-0313567-B1 AQUEOUS COMPOSITIONS CONTAINING CARBOXYLIC SALTS The Lubrizol Corporation (US) 1992-10-21 EP disclosed
EP-0473746-A1 TWO-CYCLE ENGINE FUEL COMPOSITION The Lubrizol Corporation (US) 1992-03-11 EP disclosed
WO-1991013950-A1 TWO-CYCLE ENGINE FUEL COMPOSITION THE LUBRIZOL CORPORATION (US) 1991-09-19 WO disclosed
EP-0352314-A1 EXPLOSIVE COMPOSITIONS USING A COMBINATION OF EMULSIFYING SALTS. LUBRIZOL CORP (US) 1990-01-31 EP disclosed
WO-1989009812-A1 LUBRICATING OIL ADDITIVES THE LUBRIZOL CORPORATION (US) 1989-10-19 WO disclosed
WO-1989005785-A1 EXPLOSIVE COMPOSITIONS USING A COMBINATION OF EMULSIFYING SALTS THE LUBRIZOL CORPORATION (US) 1989-06-29 WO disclosed
EP-0313567-A1 AQUEOUS COMPOSITIONS CONTAINING CARBOXYLIC SALTS. LUBRIZOL CORP (US) 1989-05-03 EP disclosed
US-4770803-A WATER BASED FUNCTIONAL FLUIDS, I.E. LUBRICANTS, HYDRAULIC FLUIDS, CUTTING FLUIDS THE LUBRIZOL CORPORATION (US) 1988-09-13 US disclosed
WO-1988000233-A1 AQUEOUS COMPOSITIONS CONTAINING CARBOXYLIC SALTS THE LUBRIZOL CORPORATION (US) 1988-01-14 WO disclosed