Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Phenylphosphonic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.76 |
| ▸ | CA4 | P22748 | 1/20 | 0.76 |
| ▸ | CA5A | P35218 | 1/20 | 0.76 |
| ▸ | CFTR | P13569 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenylphosphonic Acid SCHEMBL2790969 | 0.90 | CA2 (0.94) | CA2CA4CA5ACFTRALDH1A1 | |
| Phenylphosphonic Acid SCHEMBL11707549 | 0.89 | CA2 (0.67) | CA2CA4CA5ACFTRALDH1A1 | |
| Phenylphosphonic Acid SCHEMBL28151870 | 0.87 | CA2 (1.00) | CA2CA4CA5ACFTRALDH1A1 | |
| Phenylphosphonic Acid SCHEMBL269853 | 0.87 | CA2 (1.00) | CA2CA4CA5ACFTRALDH1A1 | |
| Phenylphosphonic Acid SCHEMBL34998 | 0.87 | CA2 (1.00) | CA2CA4CA5ACFTRALDH1A1 | |
| Phenylphosphonic Acid SCHEMBL11086096 | 0.85 | CA2 (0.94) | CA2CA4CA5ACFTRALDH1A1 | |
| Phenylphosphonic Acid SCHEMBL3397814 | 0.85 | CA2 (0.94) | CA2CA4CA5ACFTRALDH1A1 | |
| Phenylphosphonic Acid SCHEMBL109137 | 0.85 | CA2 (0.94) | CA2CA4CA5ACFTRALDH1A1 | |
| Phenylphosphonic Acid SCHEMBL2471813 | 0.85 | CA2 (0.94) | CA2CA4CA5ACFTRALDH1A1 | |
| Phenylphosphonic Acid SCHEMBL4433564 | 0.85 | CA2 (0.94) | CA2CA4CA5ACFTRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-9255693-A | — | — | None | — | — | JP | disclosed |
| JP-H09255693-A | ETHYLENEDIAMINE-PHENYLPHOSPHONIC ACID SALT, ITS PRODUCTION AND FLAME-RETARDANT RESIN COMPOSITION COMPOUNDED WITH THE SAME | TOSOH CORP | 1997-09-30 | — | — | JP | disclosed |