Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 5/20 | 0.54 |
| ▸ | GABRA5 | P31644 | 5/20 | 0.54 |
| ▸ | GABRA3 | P34903 | 5/20 | 0.54 |
| ▸ | GABRA2 | P47869 | 5/20 | 0.54 |
| ▸ | GABRB2 | P47870 | 5/20 | 0.54 |
| ▸ | GABRG2 | P18507 | 4/20 | 0.54 |
| ▸ | GABRB3 | P28472 | 4/20 | 0.54 |
| ▸ | GABRP | O00591 | 3/20 | 0.54 |
| ▸ | GABRD | O14764 | 3/20 | 0.54 |
| ▸ | GABRB1 | P18505 | 3/20 | 0.54 |
| ▸ | GABRA4 | P48169 | 3/20 | 0.54 |
| ▸ | GABRE | P78334 | 3/20 | 0.54 |
| ▸ | GABRA6 | Q16445 | 3/20 | 0.54 |
| ▸ | GABRG1 | Q8N1C3 | 3/20 | 0.54 |
| ▸ | GABRG3 | Q99928 | 3/20 | 0.54 |
| ▸ | GABRQ | Q9UN88 | 3/20 | 0.54 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7315953 | 0.84 | GABRA1 (0.60) | GABRA1GABRA5GABRA3GABRA2GABRB2 | |
| SCHEMBL5432261 | 0.82 | GABRA1 (0.61) | GABRA1GABRA5GABRA3GABRA2GABRB2 | |
| SCHEMBL9384372 | 0.82 | GABRA1 (0.57) | GABRA1GABRA5GABRA3GABRA2GABRB2 | |
| SCHEMBL9672477 | 0.80 | GABRA1 (0.52) | GABRA1GABRA5GABRA3GABRA2GABRB2 | |
| SCHEMBL8668139 | 0.79 | GAA (0.65) | GABRA1GABRA5GABRA3GABRA2GABRB2 | |
| SCHEMBL9674417 | 0.79 | GABRA1 (0.51) | GABRA1GABRA5GABRA3GABRA2GABRB2 | |
| SCHEMBL9674505 | 0.76 | GABRA1 (0.47) | GABRA1GABRA5GABRA3GABRA2GABRB2 | |
| SCHEMBL10045709 | 0.75 | GABRA1 (0.72) | GABRA1GABRA5GABRA3GABRA2GABRB2 | |
| SCHEMBL9379921 | 0.75 | GABRA1 (0.57) | GABRA1GABRA5GABRA3GABRA2GABRB2 | |
| SCHEMBL9672107 | 0.75 | GABRA1 (0.55) | GABRA1GABRA5GABRA3GABRA2GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0776892-A1 | THIENYLAZOLE COMPOUND AND THIENOTRIAZOLODIAZEPINE COMPOUND | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1997-06-04 | — | — | EP | disclosed |