⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21338352 | 1.00 | — | — | |
| Trifluoroacetic Acid SCHEMBL28575749 | 0.87 | L3MBTL1 (0.37) | — | |
| SCHEMBL30693669 | 0.87 | L3MBTL1 (0.59) | — | |
| SCHEMBL27774970 | 0.87 | L3MBTL1 (0.59) | — | |
| SCHEMBL1653739 | 0.85 | L3MBTL1 (0.53) | — | |
| SCHEMBL24108598 | 0.79 | — | — | |
| SCHEMBL28051654 | 0.79 | — | — | |
| SCHEMBL149411 | 0.79 | — | — | |
| SCHEMBL28528864 | 0.77 | — | — | |
| SCHEMBL11674331 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3994134-B9 | PROCESS FOR MANUFACTURING (S)-3-HYDROXY-1-(1H-INDOL-5-YL)-2-OXO-PYRROLIDINE-3-CARBOXYLIC ACID 3,5-DIFLUORO-BENZYLAMIDE | MERCK PATENT GMBH (DE) | 2024-06-26 | — | — | EP | claimed |
| EP-3994134-B1 | PROCESS FOR MANUFACTURING (S)-3-HYDROXY-1-(1H-INDOL-5-YL)-2-OXO-PYRROLIDINE-3-CARBOXYLIC ACID 3,5-DIFLUORO-BENZYLAMIDE | MERCK PATENT GMBH (DE) | 2024-01-24 | — | — | EP | claimed |
| EP-3976599-A1 | PYRAZOLE-SUBSTITUTED PYRROLIDINONES AS HERBICIDES | FMC CORPORATION (US) | 2022-04-06 | — | — | EP | claimed |
| EP-3728217-A1 | CHROMENOPYRIDINE DERIVATIVES AS PHOSPHATIDYLINOSITOL PHOSPHATE KINASE INHIBITORS | Ravenna Pharmaceuticals, Inc. (US) | 2020-10-28 | — | — | EP | claimed |
| US-10093623-B2 | Cyclic amides as MetAP-2 inhibitors | MERCK PATENT GMBH (DE) | 2018-10-09 | — | — | US | claimed |
| US-20040019046-A1 | Phenylacetamido-pyrazole derivatives and their use as antitumor agents | PHARMACIA ITALIA SPA (IT) | 2004-01-29 | — | — | US | claimed |
| US-12454523-B2 | Pyrazole derivatives | SYNGENTA CROP PROTECTION AG (CH) | 2025-10-28 | — | — | US | disclosed |
| US-20250179045-A1 | LPAR1 ANTAGONISTS AND USES THEREOF | CONTINEUM THERAPEUTICS, INC. | 2025-06-05 | — | — | US | disclosed |
| EP-4447681-A2 | COMPOUNDS USEFUL FOR THE PREPARATION OF VARIOUS AGROCHEMICALS AND MARKERS THEREOF | Adama Agan Ltd. (IL) | 2024-10-23 | — | — | EP | disclosed |
| US-12077525-B2 | Herbicidal compounds | SYNGENTA CROP PROTECTION AG (CH) | 2024-09-03 | — | — | US | disclosed |
| CN-117700363-A | Pyrazole derivatives | 先正达农作物保护股份公司 | 2024-03-15 | — | — | CN | disclosed |
| CN-117683024-A | Pyrazole derivatives | 先正达农作物保护股份公司 | 2024-03-12 | — | — | CN | disclosed |
| CN-117658988-A | Pyrazole derivatives | 先正达农作物保护股份公司 | 2024-03-08 | — | — | CN | disclosed |
| WO-2011068927-A2 | 11-β-HYDROXYSTEROID DEHYDROGENASE TYPE 1 (11B-HSD1) INHIBITORS AND USES THEREOF | ABBOTT LABORATORIES (US) | 2011-06-09 | — | — | WO | disclosed |
| US-7067549-B2 | Pyrrolidone carboxamides | ACTELION PHARMACEUTICALS AG (CH) | 2006-06-27 | — | — | US | disclosed |
| US-20050192292-A1 | Pyrrolidone carboxamides | ACTELION PHARMACEUTICALS AG (CH) | 2005-09-01 | — | — | US | disclosed |
| US-6784197-B2 | SUCH AS (2S)-2-((4S)-4-(2,2-DIFLUOROVINYL)-2-OXOPYRROLIDINYL) BUTANAMIDE; ANTIEPILEPTIC AGENTS; ANTICONVULSANTS | UCB S.A. (BE) | 2004-08-31 | — | — | US | disclosed |
| US-20040019046-A1 | Phenylacetamido-pyrazole derivatives and their use as antitumor agents | PHARMACIA ITALIA SPA (IT) | 2004-01-29 | — | — | US | disclosed |
| EP-1345909-A1 | PHENYLACETAMIDO-PYRAZOLE DERIVATIVES AND THEIR USE AS ANTITUMOR AGENTS | Pharmacia Italia S.p.A. (IT) | 2003-09-24 | — | — | EP | disclosed |
| WO-2002048114-A1 | PHENYLACETAMIDO- PYRAZOLE DERIVATIVES AND THEIR USE AS ANTITUMOR AGENTS | PHARMACIA ITALIA S.P.A. (IT) | 2002-06-20 | — | — | WO | disclosed |