Pyrrolidine

Pyrrolidine

SCHEMBL8928607

C1CCNC1.C1CCNC1.CC

nearest known ligand 0.80

Full drug profile on Sugi Atlas →

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.73
CXCR4 P61073 1/20 0.58
SMN1; SMN2 Q16637 1/20 0.58
HIF1A Q16665 1/20 0.46
MAPT P10636 1/20 0.46
PDE4A P27815 1/20 0.46
KDR P35968 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pyrrolidine SCHEMBL2724963 1.00
Piperidine SCHEMBL10008663 0.95 ALDH1A1 (0.82) ALDH1A1CXCR4SMN1; SMN2HIF1AMAPT
Pyrrolidine SCHEMBL9780375 0.95
Piperidine SCHEMBL11714957 0.95
Piperidine SCHEMBL11830723 0.91
Piperidine SCHEMBL27628440 0.91
Pyrrolidine SCHEMBL622433 0.89
SCHEMBL3811182 0.89 ALDH1A1 (0.89) ALDH1A1CXCR4SMN1; SMN2HIF1AMAPT
SCHEMBL576640 0.89 ALDH1A1 (0.89) ALDH1A1CXCR4SMN1; SMN2HIF1AMAPT
Pyrrolidine SCHEMBL148449 0.89

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107922678-B Dilithium initiators 飞纳技术有限公司 2020-04-07 CN disclosed
US-5691420-A STAR POLYMER; CONTAINING STYRENE, BUTADIENE AND ISOPRENE UNITS; ADHESIVES, COATINGS, SEALS SHELL OIL COMPANY (US) 1997-11-25 US disclosed