⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL893425 | 0.85 | — | — | |
| SCHEMBL893048 | 0.83 | TSHR (0.61) | — | |
| SCHEMBL7293281 | 0.81 | TSHR (0.58) | — | |
| SCHEMBL7284593 | 0.81 | TSHR (0.58) | — | |
| SCHEMBL7282104 | 0.81 | TSHR (0.58) | — | |
| SCHEMBL8811115 | 0.81 | TSHR (0.58) | — | |
| SCHEMBL893479 | 0.81 | TSHR (0.58) | — | |
| SCHEMBL4287025 | 0.81 | TSHR (0.58) | — | |
| SCHEMBL8814157 | 0.81 | TSHR (0.58) | — | |
| SCHEMBL8812278 | 0.81 | TSHR (0.58) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 366 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118159542-A | Substituted 2, 3-dihydro [1,3] thiazolo [4,5-b ] pyridines, salts thereof and their use as herbicidal agents | 拜耳公司 | 2024-06-07 | — | — | CN | claimed |
| US-8513407-B2 | Process for the preparation of N-acyl-(epi)K5-amine-O-sulfate-derivatives and products thus obtained | GLYCORES 2000 S.R.L. (IT) | 2013-08-20 | — | — | US | claimed |
| US-8357675-B2 | 17-alpha-substituted derivatives of estradiol with wound-healing activity | EUTICALS S.P.A. (IT) | 2013-01-22 | — | — | US | claimed |
| US-8034936-B2 | Spirocyclic cyclohexane compounds useful to treat substance dependency | GRUENENTHAL GMBH (DE) | 2011-10-11 | — | — | US | claimed |
| JP-4709387-B2 | — | — | 2011-06-22 | — | — | JP | claimed |
| JP-4709386-B2 | — | — | 2011-06-22 | — | — | JP | claimed |
| US-20110053970-A1 | Spirocyclic Cyclohexane Compounds Useful To Treat Substance Dependency | GRUENENTHAL GMBH (DE) | 2011-03-03 | — | — | US | claimed |
| EP-1150676-B1 | ACYL DERIVATIVES OF 4-DEMETHYLPENCLOMEDINE, USE THEREOF AND PREPARATION THEREOF | SOUTHERN RES INST (US) | 2010-08-11 | — | — | EP | claimed |
| EP-1506175-B1 | N-SUBSTITUTED TRICYCLIC 3-AMINOPYRAZOLES AS PDGF RECEPTOR INHIBITORS | JANSSEN PHARMACEUTICA NV (BE) | 2009-04-01 | — | — | EP | claimed |
| EP-1014962-A4 | ANTITHROMBOTIC AGENTS | LILLY CO ELI (US) | 2007-06-27 | — | — | EP | claimed |
| WO-1996030353-A1 | REVERSIBLE PROTEASE INHIBITORS | ARRIS PHARMACEUTICAL CORPORATION (US) | 1996-10-03 | — | — | WO | claimed |
| EP-0315367-B1 | Polypeptides | ICI PLC (GB) | 1994-04-06 | — | — | EP | claimed |
| US-5068222-A | Polypeptides for treatment of cancer | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-11-26 | — | — | US | claimed |
| US-5008290-A | Anticoagulant | DR. KARL THOMAE GMBH (DE) | 1991-04-16 | — | — | US | claimed |
| EP-0315367-A2 | Polypeptides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1989-05-10 | — | — | EP | claimed |
| EP-0262395-A2 | Sulfonamido-ethyl compounds, medicines containing them and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1988-04-06 | — | — | EP | claimed |
| EP-0162877-A1 | Method to titrate enzymes. | FLORK MICHEL (FR) | 1985-12-04 | — | — | EP | claimed |
| WO-1985002404-A1 | NEW PEPTIDE DERIVATIVES, PREPARATION PROCESS THEREOF AND UTILIZATION THEREOF AS BIOLOGICAL REAGENTS | FLORK MICHEL | 1985-06-06 | — | — | WO | claimed |
| US-4419522-A | ANTITUMOR AGENTS | CHINOIN GYOGYSZER VEGYESZETI TERMEKEK GYARA RT. (HU) | 1983-12-06 | — | — | US | claimed |
| US-3976633-A | ANORECTIC, ANTIOBESITY | SMITHKLINE CORPORATION (US) | 1976-08-24 | — | — | US | claimed |