Sugi Predict

Sugi Predict / Compounds / SCHEMBL893479

SCHEMBL893479

SCHEMBL893479

COC(=O)CCCCCCCC[C]=O

nearest known ligand 0.58

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ TSHR P16473 3/20 0.58
▸ LMNA P02545 2/20 0.52
▸ ALDH1A1 P00352 1/20 0.52
▸ L3MBTL1 Q9Y468 1/20 0.45
▸ KMT2A Q03164 3/20 0.43
▸ RECQL P46063 1/20 0.42
▸ EPHX2 P34913 4/20 0.40
▸ HPGD P15428 1/20 0.39
▸ POLB P06746 1/20 0.39
▸ POLA1 P09884 1/20 0.39
▸ MEN1 O00255 2/20 0.39
▸ PABPC1 P11940 1/20 0.39
▸ APOBEC3A P31941 1/20 0.39
▸ APOBEC3G Q9HC16 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8812278 1.00 TSHR (0.58) TSHRLMNAALDH1A1L3MBTL1KMT2A
SCHEMBL7293281 1.00 TSHR (0.58) TSHRLMNAALDH1A1L3MBTL1KMT2A
SCHEMBL8811910 1.00 TSHR (0.58) TSHRLMNAALDH1A1L3MBTL1KMT2A
SCHEMBL7284593 1.00 TSHR (0.58) TSHRLMNAALDH1A1L3MBTL1KMT2A
SCHEMBL4287025 1.00 TSHR (0.58) TSHRLMNAALDH1A1L3MBTL1KMT2A
SCHEMBL8814157 1.00 TSHR (0.58) TSHRLMNAALDH1A1L3MBTL1KMT2A
SCHEMBL8811115 1.00 TSHR (0.58) TSHRLMNAALDH1A1L3MBTL1KMT2A
SCHEMBL7282104 1.00 TSHR (0.58) TSHRLMNAALDH1A1L3MBTL1KMT2A
SCHEMBL893048 0.98 TSHR (0.61) TSHRLMNAALDH1A1L3MBTL1KMT2A
SCHEMBL893425 0.91 — —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030120077-A1 Hydroxy substituted N-alkoxy hindered amines and compositions stabilized therewith GALBO JAMES PETER (US) 2003-06-26 — — US claimed
US-6403681-B2 STABILIZER FOR PLASTICS CIBA SPECIALTY CHEMICALS CORPORATION 2002-06-11 — — US claimed
US-20020058735-A1 Hydroxy-substituted N-alkoxy hindered amines and compositions stabilized therewith GALBO JAMES PETER (US) 2002-05-16 — — US claimed
US-20020040145-A1 Hydroxy-substituted N-alkoxy hindered amines and compositions stabilized therewith GALBO JAMES P (US) 2002-04-04 — — US claimed
US-20010034449-A1 Hydroxy-substituted N-Alkoxy hindered amines and compositions stabilized therewith GALBO JAMES P (US) 2001-10-25 — — US claimed
US-20010031872-A1 Hydroxy-substituted N-Alkoxy hindered amines and compositions stabilized therewith GALBO JAMES P (US) 2001-10-18 — — US claimed
US-6271377-B1 Hydroxy-substituted N-alkoxy hindered amines and compositions stabilized therewith CIBA SPECIALTY CHEMICALS CORPORATION 2001-08-07 — — US claimed
US-6391949-B1 — — None — — US disclosed
EP-2440524-A1 STERICALLY HINDERED AMINE STABILIZERS BASF SE (DE) 2012-04-18 — — EP disclosed
US-20120083557-A1 STERICALLY HINDERED AMINE STABILIZERS BASF SE (DE) 2012-04-05 — — US disclosed
WO-2010142572-A1 STERICALLY HINDERED AMINE STABILIZERS BASF SE (DE) 2010-12-16 — — WO disclosed
US-6872832-B2 Hydroxy substituted N-alkoxy hindered amines and compositions stabilized therewith CIBA SPECIALTY CHEMICALS CORPORATION (US) 2005-03-29 — — US disclosed
US-6586507-B2 For stabilizing polyolefins, especially thermoplastic polyolefins, against the deleterious effects of oxidative, thermal and actinic radiation, also for stabilizing acid catalyzed and ambient cured coatings systems CIBA SPECIALTY CHEMICALS CORPORATION 2003-07-01 — — US disclosed
EP-0456039-A2 Renin inhibiting amino acid derivatives MERCK PATENT GmbH (DE) 1991-11-13 — — EP disclosed
EP-0446485-A2 Peptide analogues with renininhibiting activity MERCK PATENT GmbH (DE) 1991-09-18 — — EP disclosed
EP-0446751-A1 Glycolic acid derivatives MERCK PATENT GmbH (DE) 1991-09-18 — — EP disclosed
EP-0418696-A2 Derivatives of aminoacids MERCK PATENT GmbH (DE) 1991-03-27 — — EP disclosed
CN-1037155-A Amino acid derivative MERCK PATENT GMBH (DE) 1989-11-15 — — CN disclosed
EP-0339483-A2 Renin inhbiting amino-acid derivatives MERCK PATENT GmbH (DE) 1989-11-02 — — EP disclosed
EP-0337334-A2 Renin-inhibiting amino acid derivatives MERCK PATENT GmbH (DE) 1989-10-18 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020040145-A1 Hydroxy-substituted N-alkoxy hindered amines and compositions stabilized therewith POLH, OGG1, OGFOD1 TSHR 4485/4885LMNA 764/4885ALDH1A1 1091/4885
US-20120083557-A1 STERICALLY HINDERED AMINE STABILIZERS AAAS, H1-5, H1-2 TSHR 3145/4885LMNA 1890/4885ALDH1A1 496/4885
US-20020058735-A1 Hydroxy-substituted N-alkoxy hindered amines and compositions stabilized therewith OGG1, HAO2, POLH TSHR 4399/4885LMNA 507/4885ALDH1A1 689/4885
US-20010034449-A1 Hydroxy-substituted N-Alkoxy hindered amines and compositions stabilized therewith POLH, OGG1, OGFOD1 TSHR 4485/4885LMNA 764/4885ALDH1A1 1091/4885
US-20030120077-A1 Hydroxy substituted N-alkoxy hindered amines and compositions stabilized therewith OGG1, POLH, OGFOD1 TSHR 4505/4885LMNA 419/4885ALDH1A1 825/4885
US-20010031872-A1 Hydroxy-substituted N-Alkoxy hindered amines and compositions stabilized therewith POLH, OGG1, OGFOD1 TSHR 4485/4885LMNA 764/4885ALDH1A1 1091/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.