SCHEMBL892881

SCHEMBL892881

N[C@H](C(=O)C(=O)CNC(=O)OCC1c2ccccc2-c2ccccc21)[C@@H](O)[C@H](O)[C@H](O)CO

nearest known ligand 0.47

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.46
EPHX2 P34913 1/20 0.41
CASP3 P42574 4/20 0.40
OPRD1 P41143 1/20 0.38
MDM4 O15151 1/20 0.36
TP53 P04637 1/20 0.36
FABP7 O15540 1/20 0.35
FABP5 Q01469 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1595033 0.82 KMT2A (0.52) KMT2AEPHX2CASP3MDM4TP53
SCHEMBL16453926 0.78 KMT2A (0.54) KMT2AEPHX2CASP3OPRD1MDM4
SCHEMBL892879 0.78 KMT2A (0.44) KMT2AEPHX2CASP3OPRD1MDM4
SCHEMBL6239792 0.76 KMT2A (0.49) KMT2AEPHX2CASP3MDM4TP53
SCHEMBL16140731 0.75 KMT2A (0.63) KMT2AEPHX2CASP3OPRD1FABP7
SCHEMBL30697177 0.75 KMT2A (0.63) KMT2AEPHX2CASP3OPRD1FABP7
SCHEMBL13010967 0.75 MDM4 (0.48) KMT2AEPHX2CASP3MDM4TP53
SCHEMBL13984381 0.75 MDM4 (0.48) KMT2AEPHX2CASP3MDM4TP53
SCHEMBL17830013 0.75 MDM4 (0.48) KMT2AEPHX2CASP3MDM4TP53
SCHEMBL21320276 0.75 KMT2A (0.58) KMT2AEPHX2CASP3MDM4TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018115309-A1 PREPARATION OF SUGAR-NUCLEOTIDES NOVO NORDISK A/S (DK) 2018-06-28 WO disclosed
US-8841439-B2 Nucleotide sugar purification using membranes NOVO NORDISK A/S (DK) 2014-09-23 US disclosed
US-20120083600-A1 NUCLEOTIDE SUGAR PURIFICATION USING MEMBRANES NOVO NORDISK A/S (DK) 2012-04-05 US disclosed
US-20090048440-A1 Nucleotide Sugar Purification Using Membranes NEOSE TECHNOLOGIES, INC. (US) 2009-02-19 US disclosed
WO-2007056191-A2 NUCLEOTIDE SUGAR PURIFICATION USING MEMBRANES NEOSE TECHNOLOGIES, INC. (US) 2007-05-18 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120083600-A1 NUCLEOTIDE SUGAR PURIFICATION USING MEMBRANES SLC35B2, SLC35A1, GALNT1 KMT2A 3014/4885EPHX2 3834/4885CASP3 4800/4885
US-20090048440-A1 Nucleotide Sugar Purification Using Membranes SLC35B2, SLC35A1, GALNT1 KMT2A 3014/4885EPHX2 3834/4885CASP3 4800/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.