SCHEMBL1595033

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL12703680	0.86	KMT2A (0.55)	KMT2AEPHX2CASP3MDM4TP53
	SCHEMBL31396078	0.83	KMT2A (0.43)	KMT2AEPHX2CASP3FABP7FABP5
	SCHEMBL18981796	0.83	KMT2A (0.43)	KMT2AEPHX2CASP3FABP7FABP5
	SCHEMBL38662522	0.82	TLR2 (0.62)	KMT2ACASP3MDM4TP53TLR2
	SCHEMBL27442611	0.82	TLR2 (0.62)	KMT2ACASP3MDM4TP53TLR2
	SCHEMBL3890833	0.82	KMT2A (0.45)	KMT2AEPHX2CASP3TLR2
	SCHEMBL892881	0.82	KMT2A (0.46)	KMT2AEPHX2CASP3FABP7FABP5
	SCHEMBL13984381	0.82	MDM4 (0.48)	KMT2AEPHX2CASP3MDM4TP53
	SCHEMBL13010967	0.82	MDM4 (0.48)	KMT2AEPHX2CASP3MDM4TP53
	SCHEMBL17830013	0.82	MDM4 (0.48)	KMT2AEPHX2CASP3MDM4TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.