SCHEMBL8929992

SCHEMBL8929992

[O]c1ccc2cccc3c2c1C=CC3

nearest known ligand 0.41

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.41
TSHR P16473 2/20 0.41
ALDH1A1 P00352 3/20 0.36
HPGD P15428 3/20 0.36
CYP1A2 P05177 2/20 0.36
HSD17B10 Q99714 2/20 0.36
KDM4E B2RXH2 2/20 0.36
TYMS P04818 1/20 0.36
CYP2C19 P33261 1/20 0.36
CYP1A1 P04798 1/20 0.34
CYP1B1 Q16678 1/20 0.34
PARP1 P09874 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10542837 0.81 TSHR (0.43) CYP3A4TSHRALDH1A1HPGDCYP1A2
SCHEMBL20377849 0.79 CYP3A4 (0.41) CYP3A4TSHRALDH1A1HPGDCYP1A2
SCHEMBL28418222 0.79 CYP3A4 (0.41) CYP3A4TSHRALDH1A1HPGDCYP1A2
SCHEMBL27722276 0.79 CYP3A4 (0.41) CYP3A4TSHRALDH1A1HPGDCYP1A2
SCHEMBL23668366 0.79 CYP3A4 (0.41) CYP3A4TSHRALDH1A1HPGDCYP1A2
SCHEMBL23546524 0.79 CYP3A4 (0.41) CYP3A4TSHRALDH1A1HPGDCYP1A2
SCHEMBL3948797 0.79 CYP3A4 (0.41) CYP3A4TSHRALDH1A1HPGDCYP1A2
SCHEMBL25429169 0.79 TSHR (0.41) CYP3A4TSHRALDH1A1HPGDCYP1A2
SCHEMBL3700917 0.79 CYP3A4 (0.41) CYP3A4TSHRALDH1A1HPGDCYP1A2
SCHEMBL27755130 0.79 CYP3A4 (0.41) CYP3A4TSHRALDH1A1HPGDCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5530090-A Reductive method for preparation of macrocyclic oligomer mixtures GENERAL ELECTRIC COMPANY (US) 1996-06-25 US claimed
JP-9003192-A None JP disclosed
JP-H093192-A REDUCTION METHOD FOR PREPARING LARGE CYCLIC OLIGOMER MIXTURE GENERAL ELECTRIC CO <GE> 1997-01-07 JP disclosed