Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | HK2 | P52789 | 6/20 | 0.53 |
| ▸ | HK1 | P19367 | 5/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | ASGR1 | P07306 | 1/20 | 0.41 |
| ▸ | PYGB | P11216 | 6/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14520981 | 1.00 | KDM4E (0.54) | KDM4ELMNACYP2D6CYP2C19HK2 | |
| SCHEMBL15965649 | 1.00 | KDM4E (0.54) | KDM4ELMNACYP2D6CYP2C19HK2 | |
| SCHEMBL15966250 | 1.00 | KDM4E (0.54) | KDM4ELMNACYP2D6CYP2C19HK2 | |
| SCHEMBL15966292 | 1.00 | KDM4E (0.54) | KDM4ELMNACYP2D6CYP2C19HK2 | |
| SCHEMBL12371561 | 1.00 | KDM4E (0.54) | KDM4ELMNACYP2D6CYP2C19HK2 | |
| SCHEMBL17210624 | 1.00 | KDM4E (0.54) | KDM4ELMNACYP2D6CYP2C19HK2 | |
| SCHEMBL15966273 | 1.00 | KDM4E (0.54) | KDM4ELMNACYP2D6CYP2C19HK2 | |
| SCHEMBL15590477 | 1.00 | KDM4E (0.54) | KDM4ELMNACYP2D6CYP2C19HK2 | |
| SCHEMBL21753475 | 1.00 | KDM4E (0.54) | KDM4ELMNACYP2D6CYP2C19HK2 | |
| SCHEMBL13012256 | 1.00 | KDM4E (0.54) | KDM4ELMNACYP2D6CYP2C19HK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-3081282-A | — | — | None | — | — | JP | disclosed |
| WO-1997014709-A1 | ANTISENSE OLIGOMERS | F. HOFFMANN-LA ROCHE AG (CH) | 1997-04-24 | — | — | WO | disclosed |
| JP-H0381282-A | GLUCOSAMINE DERIVATIVE AND PRODUCTION THEREOF | YAIZU SUISAN KAGAKU KOGYO KK | 1991-04-05 | — | — | JP | disclosed |