SCHEMBL12371561

SCHEMBL12371561

O=C(N[C@H]1C(O)O[C@H](CO)[C@@H](O)[C@@H]1O)C(F)(F)F

nearest known ligand 0.54

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.54
LMNA P02545 1/20 0.54
CYP2D6 P10635 1/20 0.54
CYP2C19 P33261 1/20 0.54
HK2 P52789 6/20 0.53
HK1 P19367 5/20 0.49
MAPK1 P28482 1/20 0.43
ASGR1 P07306 1/20 0.41
PYGB P11216 6/20 0.40
GAA P10253 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14520981 1.00 KDM4E (0.54) KDM4ELMNACYP2D6CYP2C19HK2
SCHEMBL15965649 1.00 KDM4E (0.54) KDM4ELMNACYP2D6CYP2C19HK2
SCHEMBL15966250 1.00 KDM4E (0.54) KDM4ELMNACYP2D6CYP2C19HK2
SCHEMBL15966292 1.00 KDM4E (0.54) KDM4ELMNACYP2D6CYP2C19HK2
SCHEMBL17210624 1.00 KDM4E (0.54) KDM4ELMNACYP2D6CYP2C19HK2
SCHEMBL8930010 1.00 KDM4E (0.54) KDM4ELMNACYP2D6CYP2C19HK2
SCHEMBL15966273 1.00 KDM4E (0.54) KDM4ELMNACYP2D6CYP2C19HK2
SCHEMBL15590477 1.00 KDM4E (0.54) KDM4ELMNACYP2D6CYP2C19HK2
SCHEMBL21753475 1.00 KDM4E (0.54) KDM4ELMNACYP2D6CYP2C19HK2
SCHEMBL13012256 1.00 KDM4E (0.54) KDM4ELMNACYP2D6CYP2C19HK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250163091-A1 FUNCTIONALIZED HUMAN MILK OLIGOSACCHARIDES AND METHODS FOR PRODUCING THEM THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2025-05-22 US claimed
CN-113832136-B Mn-ZIF-90 immobilized Nahk-based composite catalytic material and preparation method and application thereof 南京师范大学 2024-03-26 CN claimed
WO-2023141513-A2 FUNCTIONALIZED HUMAN MILK OLIGOSACCHARIDES AND METHODS FOR PRODUCING THEM THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2023-07-27 WO claimed
WO-2023280235-A1 HEPARIN MOLECULE CONTAINING AT BINDING SEQUENCE AND CONTINUOUS 2-O-GLUCURONIC ACID RESIDUE, AND PREPARATION METHOD THEREFOR AND USE THEREOF 山东大学 2023-01-12 WO claimed
CN-114703242-A Double-enzyme co-immobilization synthesis method of uridine diphosphate-N-acetylglucosamine and derivatives thereof 山东大学 2022-07-05 CN claimed
CN-113832136-A Mn-ZIF-90 immobilized NaHk-based composite catalytic material and preparation method and application thereof 南京师范大学 2021-12-24 CN claimed
CN-105452479-B Reversible heparin molecules 北卡罗来纳大学查珀尔希尔分校 2021-05-18 CN claimed
CN-121499684-A High performance liquid phase analysis method for N-acetyl-glucosamine and N-trifluoroacetyl-glucosamine 安徽合城生物医药科技有限公司 2026-02-10 CN disclosed
CN-121499684-A High performance liquid phase analysis method for N-acetyl-glucosamine and N-trifluoroacetyl-glucosamine 安徽合城生物医药科技有限公司 2026-02-10 CN disclosed
US-20250195689-A1 GLYCOMIMETIC LIGANDS AVICEDA THERAPEUTICS, INC. 2025-06-19 US disclosed
US-20250188506-A1 ANTICOAGULANT HEPARIN-CHONDROITIN CHIMERIC SACCHARIDE MOLECULE AS WELL AS PREPARATION METHOD AND APPLICATION THEREOF SHANDONG UNIVERSITY (CN) 2025-06-12 US disclosed
CN-116622006-B Short acting heparin-based anticoagulant compounds and methods 北卡罗来纳大学查珀尔希尔分校 2025-05-30 CN disclosed
US-20250163091-A1 FUNCTIONALIZED HUMAN MILK OLIGOSACCHARIDES AND METHODS FOR PRODUCING THEM THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2025-05-22 US disclosed
CN-114703242-A Double-enzyme co-immobilization synthesis method of uridine diphosphate-N-acetylglucosamine and derivatives thereof 山东大学 2022-07-05 CN disclosed
CN-113832136-A Mn-ZIF-90 immobilized NaHk-based composite catalytic material and preparation method and application thereof 南京师范大学 2021-12-24 CN disclosed
CN-105452479-B Reversible heparin molecules 北卡罗来纳大学查珀尔希尔分校 2021-05-18 CN disclosed
US-7994154-B2 Substituted liposaccharides useful in the treatment and prevention of endotoxemia Ersai R&D Management Co., Ltd. (JP) 2011-08-09 US disclosed
US-20100227835-A1 SUBSTITUTED LIPOSACCHARIDES USEFUL IN THE TREATMENT AND PREVENTION OF ENDOTOXEMIA EISAI R&D MANAGEMENT CO., LTD (JP) 2010-09-09 US disclosed
US-7737129-B2 Substituted liposaccharides useful in the treatment and prevention of endotoxemia EISAI R & D MANAGEMENT CO., LTD. (JP) 2010-06-15 US disclosed
US-20080214802-A1 Substituted Liposaccharides Useful in the Treatment and Prevention of Endotoxemia EISAI CO., LTD. (JP) 2008-09-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080214802-A1 Substituted Liposaccharides Useful in the Treatment and Prevention of Endotoxemia LIPG, FUT6, UGCG KDM4E 4257/4885LMNA 492/4885CYP2D6 2705/4885
US-20250195689-A1 GLYCOMIMETIC LIGANDS SIGLEC9, SIGLEC7, LGALS2 KDM4E 4635/4885LMNA 3854/4885CYP2D6 3792/4885
US-20100227835-A1 SUBSTITUTED LIPOSACCHARIDES USEFUL IN THE TREATMENT AND PREVENTION OF ENDOTOXEMIA LIPG, FUT6, UGCG KDM4E 4257/4885LMNA 492/4885CYP2D6 2705/4885
US-20250188506-A1 ANTICOAGULANT HEPARIN-CHONDROITIN CHIMERIC SACCHARIDE MOLECULE AS WELL AS PREPARATION METHOD AND APPLICATION THEREOF HPSE, CD44, CSGALNACT1 KDM4E 2166/4885LMNA 2836/4885CYP2D6 728/4885
US-20250163091-A1 FUNCTIONALIZED HUMAN MILK OLIGOSACCHARIDES AND METHODS FOR PRODUCING THEM GALNT6, GALNT2, GALNT1 KDM4E 4845/4885LMNA 2180/4885CYP2D6 2344/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.