Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 4/20 | 0.38 |
| ▸ | RAB9A | P51151 | 5/20 | 0.37 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7833221 | 0.82 | MAPK1 (0.57) | MAPK1HSD17B10KMT2AMEN1NPC1 | |
| SCHEMBL3967541 | 0.80 | MAPK1 (0.51) | MAPK1HSD17B10KMT2AMEN1NPC1 | |
| SCHEMBL3805634 | 0.80 | MAPK1 (0.51) | MAPK1HSD17B10KMT2AMEN1NPC1 | |
| SCHEMBL8930247 | 0.77 | MAPK1 (0.60) | MAPK1HSD17B10KMT2AMEN1NPC1 | |
| SCHEMBL8930172 | 0.76 | MAPK1 (0.35) | MAPK1HSD17B10KMT2AMEN1NPC1 | |
| SCHEMBL8440916 | 0.74 | MAPK1 (0.47) | MAPK1HSD17B10KMT2AMEN1NPC1 | |
| Carboxin SCHEMBL8819780 | 0.69 | MAPK1 (1.00) | MAPK1HSD17B10KMT2AMEN1NPC1 | |
| SCHEMBL7596951 | 0.69 | MAPK1 (0.58) | MAPK1HSD17B10KMT2AMEN1NPC1 | |
| SCHEMBL17471577 | 0.68 | MAPK1 (0.57) | MAPK1HSD17B10KMT2ANPC1RAB9A | |
| SCHEMBL3971431 | 0.67 | MAPK1 (0.66) | MAPK1HSD17B10KMT2AMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5693827-A | Treatment of HIV infections and compounds useful therein | UNIROYAL CHEMICAL COMPANY, INC. | 1997-12-02 | — | — | US | disclosed |