Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.43 |
| ▸ | MEN1 | O00255 | 7/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 5/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3760345 | 0.80 | HDAC4 (0.36) | MAPK1HSD17B10KMT2AMEN1NPC1 | |
| SCHEMBL669565 | 0.79 | GAA (0.45) | MAPK1HSD17B10KMT2AMEN1MAPT | |
| SCHEMBL7833221 | 0.76 | MAPK1 (0.57) | MAPK1HSD17B10KMT2AMEN1NPC1 | |
| SCHEMBL669568 | 0.74 | ALDH1A1 (0.41) | MAPK1HSD17B10KMT2AMEN1POLB | |
| SCHEMBL3967541 | 0.74 | MAPK1 (0.51) | MAPK1HSD17B10KMT2AMEN1NPC1 | |
| SCHEMBL3805634 | 0.74 | MAPK1 (0.51) | MAPK1HSD17B10KMT2AMEN1NPC1 | |
| SCHEMBL9198342 | 0.74 | KMT2A (0.70) | MAPK1HSD17B10KMT2AMEN1NPC1 | |
| SCHEMBL9198161 | 0.74 | KMT2A (0.64) | MAPK1HSD17B10KMT2AMEN1NPC1 | |
| SCHEMBL8930247 | 0.71 | MAPK1 (0.60) | MAPK1HSD17B10KMT2AMEN1NPC1 | |
| SCHEMBL11632785 | 0.71 | GAA (0.43) | MAPK1HSD17B10KMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5869427-A | Substituted thiophene derivative and plant disease control agent comprising the same as active ingredient | MITSUI CHEMICALS, INC. (JP) | 1999-02-09 | — | — | US | disclosed |
| EP-0841336-A1 | Substituted thiopene derivative and plant disease control agent comprising the same as active ingredient | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1998-05-13 | — | — | EP | disclosed |
| US-5693827-A | Treatment of HIV infections and compounds useful therein | UNIROYAL CHEMICAL COMPANY, INC. | 1997-12-02 | — | — | US | disclosed |
| EP-0497816-B1 | TREATMENT OF HIV INFECTIONS AND COMPOUNDS USEFUL THEREIN | UNIROYAL CHEMICAL LTD (CA) | 1995-05-17 | — | — | EP | disclosed |
| US-5268389-A | Containing a benzene ring | UNIROYAL CHEMICAL COMPANY, INC. (US) | 1993-12-07 | — | — | US | disclosed |
| EP-0497816-A1 | TREATMENT OF HIV INFECTIONS AND COMPOUNDS USEFUL THEREIN. | UNIROYAL CHEMICAL LTD (CA) | 1992-08-12 | — | — | EP | disclosed |
| WO-1991005761-A1 | TREATMENT OF HIV INFECTIONS AND COMPOUNDS USEFUL THEREIN | UNIROYAL CHEMICAL LTD./UNIROYAL CHEMICAL LTEE (CA) | 1991-05-02 | — | — | WO | disclosed |
| US-4230871-A | Process for preparing 5,6-dihydro-2-methyl-1,4-oxathiin derivatives | LEE WHA S | 1980-10-28 | — | — | US | disclosed |
| US-4189435-A | Process for preparing 5,6-dihydro-2-methyl-1,4-oxathiin derivatives | LEE WHA S (CA) | 1980-02-19 | — | — | US | disclosed |
| US-4152334-A | Process for preparing 5,6-dihydro-2-methyl-1,4-oxathiin derivatives | LEE WHA S | 1979-05-01 | — | — | US | disclosed |