Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOX | P28300 | 1/20 | 0.42 |
| ▸ | LOXL3 | P58215 | 1/20 | 0.42 |
| ▸ | LOXL4 | Q96JB6 | 1/20 | 0.42 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12862599 | 0.60 | LOX (0.40) | LOXLOXL3LOXL4LOXL2 | |
| SCHEMBL6471045 | 0.55 | USP2 (0.31) | — | |
| SCHEMBL10831262 | 0.49 | ALDH1A1 (0.30) | — | |
| SCHEMBL993138 | 0.48 | — | — | |
| SCHEMBL9612339 | 0.48 | MEN1 (0.35) | — | |
| SCHEMBL10351240 | 0.48 | — | — | |
| SCHEMBL200674 | 0.46 | MAPT (0.41) | LOXLOXL3LOXL4LOXL2 | |
| SCHEMBL13109317 | 0.46 | — | — | |
| SCHEMBL423439 | 0.45 | CYP3A4 (0.38) | — | |
| SCHEMBL13906871 | 0.45 | MAPT (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8188203-B2 | Intraocular lens formed from a polymer of an unsaturated aryl monoazo dye containing a 2-pyrazolin-5-one, dimedone (5,5-dimethyl-1,3-cyclohexanedione), acetoacetamide, malonamide, barbituric acid or 1,3-propanedione residue; yellow light absorbers; block ultraviolet and/or violet-blue light transmission | Abbott Medical Optics Inc. (US) | 2012-05-29 | — | — | US | disclosed |
| US-20080182957-A1 | Copolymerizable azo compounds and articles containing them | Johnson & Johnson Surgical Vision, Inc. | 2008-07-31 | — | — | US | disclosed |
| US-7326423-B2 | Copolymerizable azo compounds and articles containing them | ADVANCED MEDICAL OPTICS, INC. (US) | 2008-02-05 | — | — | US | disclosed |