Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.62 |
| ▸ | MEN1 | O00255 | 5/20 | 0.60 |
| ▸ | NPC1 | O15118 | 3/20 | 0.60 |
| ▸ | RAB9A | P51151 | 3/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.59 |
| ▸ | PKM | P14618 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | HTT | P42858 | 2/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.59 |
| ▸ | AURKA | O14965 | 1/20 | 0.59 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.59 |
| ▸ | JAK2 | O60674 | 1/20 | 0.59 |
| ▸ | GMNN | O75496 | 1/20 | 0.59 |
| ▸ | EGFR | P00533 | 1/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL520043 | 0.87 | KMT2A (0.66) | MAPTALDH1A1KMT2AMEN1RAB9A | |
| SCHEMBL30641927 | 0.87 | KMT2A (0.66) | MAPTALDH1A1KMT2AMEN1RAB9A | |
| SCHEMBL26979409 | 0.87 | RORC (0.63) | MAPTALDH1A1KMT2AMEN1NPC1 | |
| SCHEMBL4506462 | 0.85 | MAPT (0.64) | MAPTALDH1A1KMT2AMEN1NPC1 | |
| SCHEMBL4506455 | 0.85 | MAPT (0.64) | MAPTALDH1A1KMT2AMEN1NPC1 | |
| SCHEMBL9836802 | 0.85 | MAPT (0.62) | MAPTALDH1A1KMT2AMEN1NPC1 | |
| SCHEMBL11448823 | 0.85 | MAPT (0.68) | MAPTALDH1A1KMT2AMEN1NPC1 | |
| SCHEMBL11269623 | 0.84 | MAPT (0.65) | MAPTALDH1A1KMT2AMEN1NPC1 | |
| SCHEMBL11637319 | 0.83 | SMN1; SMN2 (0.57) | MAPTALDH1A1KMT2AMEN1MAPK1 | |
| SCHEMBL8407519 | 0.83 | MAPT (0.64) | MAPTALDH1A1KMT2AMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013060029-A1 | ALLOSTERIC MODULATORS OF METABOTROPIC GLUTAMATE RECEPTORS | MERCK SHARP & DOHME CORP (US) | 2013-05-02 | — | — | WO | disclosed |
| WO-2013063100-A1 | ALLOSTERIC MODULATORS OF METABOTROPIC GLUTAMATE RECEPTORS | MERCK SHARP & DOHME CORP. (US) | 2013-05-02 | — | — | WO | disclosed |
| US-20100093747-A1 | METHOD OF INDUCING NEGATIVE CHEMOTAXIS | CELTAXSYS, INC. | 2010-04-15 | — | — | US | disclosed |
| WO-1997014443-A1 | MAGNETICALLY LABELED CHEMOATTRACTANTS AS TARGETED CONTRAST AGENTS IN THE NMR IMAGING OF LIVING TISSUES | BRACCO INTERNATIONAL B.V. (NL) | 1997-04-24 | — | — | WO | disclosed |
| EP-0027646-B1 | PROCESS FOR THE PREPARATION OF BENZIMIDAZOLE DERIVATIVES | CHINOIN Gyogyszer és Vegyészeti Termékek Gyára RT. (HU) | 1984-03-07 | — | — | EP | disclosed |
| EP-0010231-B1 | POLYPHOSPHAZENE POLYMERS CONTAINING N-SUBSTITUTED AMIDO AND IMIDO SUBSTITUENTS AND PROCESS FOR THEIR PREPARATION | THE FIRESTONE TIRE & RUBBER COMPANY (US) | 1982-12-15 | — | — | EP | disclosed |
| US-4218557-A | PROTECTIVE COATINGS, MOLDINGS, FOAMS | THE FIRESTONE TIRE & RUBBER COMPANY (US) | 1980-08-19 | — | — | US | disclosed |
| EP-0010231-A1 | Polyphosphazene polymers containing N-substituted amido and imido substituents and process for their preparation | THE FIRESTONE TIRE & RUBBER COMPANY (US) | 1980-04-30 | — | — | EP | disclosed |
| US-4102924-A | REACTING ACYLAMINO-ARYLS WITH HALO-ARYLS | BAYER AKTIENGESELLSCHAFT (DE) | 1978-07-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100093747-A1 | METHOD OF INDUCING NEGATIVE CHEMOTAXIS | PMAIP1, CDC42, DCX | MAPT 4842/4885ALDH1A1 3761/4885KMT2A 4738/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.