Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.66 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.66 |
| ▸ | MEN1 | O00255 | 1/20 | 0.66 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.66 |
| ▸ | MAPT | P10636 | 8/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.59 |
| ▸ | FAAH | O00519 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18119719 | 0.85 | MAPT (0.67) | LMNAKMT2ACYP1A2MEN1TDP1 | |
| SCHEMBL26488 | 0.84 | MAPT (0.65) | LMNAKMT2ACYP1A2MEN1TDP1 | |
| SCHEMBL8930726 | 0.82 | HTT (0.64) | LMNAKMT2ACYP1A2MEN1MAPT | |
| SCHEMBL19464662 | 0.81 | LMNA (0.65) | LMNAKMT2ACYP1A2MEN1TDP1 | |
| Phenacetin SCHEMBL23280 | 0.80 | KMT2A (1.00) | LMNAKMT2ACYP1A2MEN1TDP1 | |
| Phenacetin SCHEMBL18894356 | 0.80 | KMT2A (1.00) | LMNAKMT2ACYP1A2MEN1TDP1 | |
| Phenacetin SCHEMBL28630552 | 0.78 | KMT2A (0.96) | LMNAKMT2ACYP1A2MEN1TDP1 | |
| Phenacetin SCHEMBL28388594 | 0.78 | KMT2A (0.96) | LMNAKMT2ACYP1A2MEN1TDP1 | |
| Phenacetin SCHEMBL10630698 | 0.78 | KMT2A (0.96) | LMNAKMT2ACYP1A2MEN1TDP1 | |
| Phenacetin SCHEMBL28570302 | 0.78 | KMT2A (0.96) | LMNAKMT2ACYP1A2MEN1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8188203-B2 | Intraocular lens formed from a polymer of an unsaturated aryl monoazo dye containing a 2-pyrazolin-5-one, dimedone (5,5-dimethyl-1,3-cyclohexanedione), acetoacetamide, malonamide, barbituric acid or 1,3-propanedione residue; yellow light absorbers; block ultraviolet and/or violet-blue light transmission | Abbott Medical Optics Inc. (US) | 2012-05-29 | — | — | US | disclosed |
| US-8188203-B2 | Intraocular lens formed from a polymer of an unsaturated aryl monoazo dye containing a 2-pyrazolin-5-one, dimedone (5,5-dimethyl-1,3-cyclohexanedione), acetoacetamide, malonamide, barbituric acid or 1,3-propanedione residue; yellow light absorbers; block ultraviolet and/or violet-blue light transmission | Abbott Medical Optics Inc. (US) | 2012-05-29 | — | — | US | disclosed |
| US-20080182957-A1 | Copolymerizable azo compounds and articles containing them | Johnson & Johnson Surgical Vision, Inc. | 2008-07-31 | — | — | US | disclosed |
| US-20080182957-A1 | Copolymerizable azo compounds and articles containing them | Johnson & Johnson Surgical Vision, Inc. | 2008-07-31 | — | — | US | disclosed |
| US-7326423-B2 | Copolymerizable azo compounds and articles containing them | ADVANCED MEDICAL OPTICS, INC. (US) | 2008-02-05 | — | — | US | disclosed |
| US-7326423-B2 | Copolymerizable azo compounds and articles containing them | ADVANCED MEDICAL OPTICS, INC. (US) | 2008-02-05 | — | — | US | disclosed |