Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7473579 | 0.80 | GLP1R (0.35) | HSD17B10 | |
| SCHEMBL8488634 | 0.79 | KDM4E (0.31) | ALDH1A1HSD17B10 | |
| SCHEMBL8487042 | 0.76 | GRIN1 (0.34) | — | |
| SCHEMBL8650855 | 0.71 | GRIN1 (0.42) | KMT2A | |
| SCHEMBL7476576 | 0.71 | GRIN1 (0.35) | — | |
| SCHEMBL7470542 | 0.71 | GRIN1 (0.39) | KMT2A | |
| SCHEMBL8488510 | 0.70 | GRIN1 (0.49) | ALDH1A1MAPTKMT2A | |
| SCHEMBL7467566 | 0.70 | GRIN1 (0.39) | ALDH1A1MAPTKMT2A | |
| SCHEMBL7471935 | 0.70 | GLP1R (0.33) | — | |
| SCHEMBL7471473 | 0.70 | GRIN1 (0.34) | MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997031902-A1 | QUINOXALINE DERIVATIVES USEFUL IN THERAPY | PFIZER RESEARCH AND DEVELOPMENT COMPANY, N.V./S.A. (IE) | 1997-09-04 | — | — | WO | disclosed |