Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 16/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | GLP1R | P43220 | 1/20 | 0.31 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7464603 | 0.89 | GRIN1 (0.39) | GRIN1MEN1PKMKMT2A | |
| SCHEMBL7471711 | 0.89 | GRIN1 (0.39) | GRIN1RAB9AGLP1RHRH4 | |
| SCHEMBL7470542 | 0.88 | GRIN1 (0.39) | GRIN1GLP1RHRH4MEN1PKM | |
| SCHEMBL8930335 | 0.85 | GRIN1 (0.38) | GRIN1GLP1R | |
| SCHEMBL7467566 | 0.85 | GRIN1 (0.39) | GRIN1RAB9AMEN1PKMKMT2A | |
| SCHEMBL8488510 | 0.85 | GRIN1 (0.49) | GRIN1RAB9AMEN1PKMKMT2A | |
| SCHEMBL7471934 | 0.84 | GRIN1 (0.50) | GRIN1RAB9AGLP1RHRH4MEN1 | |
| SCHEMBL7470510 | 0.84 | RAB9A (0.46) | GRIN1RAB9AMEN1PKMKMT2A | |
| SCHEMBL7471473 | 0.84 | GRIN1 (0.34) | GRIN1RAB9AGLP1RHRH4MEN1 | |
| SCHEMBL7476576 | 0.84 | GRIN1 (0.35) | GRIN1GLP1RHRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5852016-A | Quinoxaline derivatives useful in therapy | PFIZER INC. (US) | 1998-12-22 | — | — | US | disclosed |
| EP-0783495-A1 | QUINOXALINE DERIVATIVES USEFUL IN THERAPY | Pfizer Limited (GB) | 1997-07-16 | — | — | EP | disclosed |
| WO-1996009295-A1 | QUINOXALINE DERIVATIVES USEFUL IN THERAPY | PFIZER LIMITED (GB) | 1996-03-28 | — | — | WO | disclosed |