Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 11/20 | 0.66 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | AHR | P35869 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8930728 | 0.81 | MEN1 (0.57) | MEN1KMT2APOLBMAPTLMNA | |
| SCHEMBL3831243 | 0.81 | EPHX1 (0.72) | LPAR1EPHX1MEN1KMT2APOLB | |
| SCHEMBL30388763 | 0.81 | EPHX1 (0.72) | LPAR1EPHX1MEN1KMT2APOLB | |
| SCHEMBL8930775 | 0.80 | POLB (0.58) | LPAR1MEN1KMT2APOLBMAPT | |
| SCHEMBL8930615 | 0.79 | SMN1; SMN2 (0.57) | MEN1KMT2AMAPTLMNASMN1; SMN2 | |
| SCHEMBL5923961 | 0.78 | LPAR1 (0.62) | LPAR1EPHX1MEN1KMT2APOLB | |
| SCHEMBL12339799 | 0.77 | GAA (0.58) | MEN1KMT2APOLBMAPTSMN1; SMN2 | |
| SCHEMBL28817103 | 0.77 | RAB9A (0.56) | LPAR1MEN1KMT2APOLBSMN1; SMN2 | |
| SCHEMBL29639811 | 0.76 | EPHX1 (0.61) | LPAR1EPHX1MEN1KMT2APOLB | |
| SCHEMBL10506942 | 0.76 | EPHX1 (0.61) | LPAR1EPHX1MEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8188203-B2 | Intraocular lens formed from a polymer of an unsaturated aryl monoazo dye containing a 2-pyrazolin-5-one, dimedone (5,5-dimethyl-1,3-cyclohexanedione), acetoacetamide, malonamide, barbituric acid or 1,3-propanedione residue; yellow light absorbers; block ultraviolet and/or violet-blue light transmission | Abbott Medical Optics Inc. (US) | 2012-05-29 | — | — | US | disclosed |
| US-8188203-B2 | Intraocular lens formed from a polymer of an unsaturated aryl monoazo dye containing a 2-pyrazolin-5-one, dimedone (5,5-dimethyl-1,3-cyclohexanedione), acetoacetamide, malonamide, barbituric acid or 1,3-propanedione residue; yellow light absorbers; block ultraviolet and/or violet-blue light transmission | Abbott Medical Optics Inc. (US) | 2012-05-29 | — | — | US | disclosed |
| US-20080182957-A1 | Copolymerizable azo compounds and articles containing them | Johnson & Johnson Surgical Vision, Inc. | 2008-07-31 | — | — | US | disclosed |
| US-20080182957-A1 | Copolymerizable azo compounds and articles containing them | Johnson & Johnson Surgical Vision, Inc. | 2008-07-31 | — | — | US | disclosed |
| US-7326423-B2 | Copolymerizable azo compounds and articles containing them | ADVANCED MEDICAL OPTICS, INC. (US) | 2008-02-05 | — | — | US | disclosed |
| US-7326423-B2 | Copolymerizable azo compounds and articles containing them | ADVANCED MEDICAL OPTICS, INC. (US) | 2008-02-05 | — | — | US | disclosed |