SCHEMBL8931022

SCHEMBL8931022

O=C1c2ccccc2C(=O)c2c1cccc2N(Cc1ccccc1)Cc1ccccc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PABPC1 P11940 3/20 0.62
MEN1 O00255 1/20 0.62
KMT2A Q03164 1/20 0.62
L3MBTL1 Q9Y468 6/20 0.57
MAPT P10636 5/20 0.57
TDP1 Q9NUW8 4/20 0.57
ALDH1A1 P00352 4/20 0.57
MAPK1 P28482 4/20 0.57
NSD2 O96028 2/20 0.57
EGFR P00533 2/20 0.57
LMNA P02545 1/20 0.57
NR3C1 P04150 8/20 0.49
KDM4E B2RXH2 1/20 0.47
ELANE P08246 1/20 0.45
SMN1; SMN2 Q16637 3/20 0.44
NPSR1 Q6W5P4 2/20 0.44
RAB9A P51151 2/20 0.44
NPC1 O15118 1/20 0.44
MITF O75030 1/20 0.44
THRB P10828 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24359434 0.79 MEN1 (0.76) PABPC1MEN1KMT2AL3MBTL1MAPT
SCHEMBL11312705 0.79 MEN1 (0.66) PABPC1MEN1KMT2AL3MBTL1MAPT
SCHEMBL11131636 0.77 MEN1 (0.71) PABPC1MEN1KMT2AL3MBTL1MAPT
SCHEMBL12858677 0.77 MEN1 (1.00) PABPC1MEN1KMT2AL3MBTL1MAPT
SCHEMBL9391303 0.77 KMT2A (0.62) PABPC1MEN1KMT2AL3MBTL1MAPT
SCHEMBL728510 0.75 MEN1 (0.60) PABPC1MEN1KMT2AL3MBTL1MAPT
SCHEMBL24359431 0.75 MEN1 (0.60) PABPC1MEN1KMT2AL3MBTL1MAPT
SCHEMBL9514469 0.75 ALDH1A1 (0.56) PABPC1MEN1KMT2AL3MBTL1MAPT
SCHEMBL2328263 0.74 MEN1 (0.68) PABPC1MEN1KMT2AL3MBTL1MAPT
SCHEMBL6852654 0.74 MAPT (0.47) PABPC1MEN1KMT2AL3MBTL1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-9263571-A None JP disclosed
CN-111302961-B Method for synthesizing N-aryl/alkyl anthraquinone and derivatives thereof under catalysis of carbene metal ligand 中国科学院兰州化学物理研究所 2022-06-14 CN disclosed
CN-111302961-A Method for synthesizing N-aryl/alkyl anthraquinone and derivatives thereof under catalysis of carbene metal ligand 中国科学院兰州化学物理研究所 2020-06-19 CN disclosed
JP-H09263571-A PURIFICATION OF 1-AMINO-5-BENZOYLAMINOANTHRAQUINONE MITSUI TOATSU CHEM INC 1997-10-07 JP disclosed
US-4292151-A MELT SPINNING THE BLOCK POLYMER WITH AN UNSATURATED COMPOUND; CURING WITH ACTINIC RADIATION TEIJIN LIMITED (JP) 1981-09-29 US disclosed
US-4269947-A AN AROMATIC DICARBOXYLIC ACID-ACYCLIC GLYCOL-BASED POLYESTER MODIFIED BY AN EPOXY-CONTAINING COMPOUND; IMPROVED PROPERTIES; FILMS AND FIBERS TEIJIN LIMITED (JP) 1981-05-26 US disclosed
US-4256558-A EXTRUSION OF A BLEND OF POLYETHYLENE TEREPHTHALATE AND A DIALLYL COMPOUND FOLLOWED BY RADIATION CURING; FILMS AND FILAMENTS HAVING GOOD HEAT RESISTANCE AND PHOTOSTABILITY TEIJIN LIMITED (JP) 1981-03-17 US disclosed
US-4196066-A UNSATURATED EPOXIDE TEIJIN LIMITED (JP) 1980-04-01 US disclosed
US-3948664-A ANTHRAQUINONE DYES FUJI PHOTO FILM CO., LTD. (JA) 1976-04-06 US disclosed