SCHEMBL8931023

SCHEMBL8931023

Nc1ccc2c(c1Cc1ccccc1)C(=O)c1cccc(Cc3ccccc3)c1C2=O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ELANE P08246 3/20 0.50
CTSG P08311 1/20 0.46
MAOA P21397 2/20 0.44
MAOB P27338 2/20 0.44
ADORA2A P29274 3/20 0.42
CSNK1A1 P48729 2/20 0.42
CSNK1D P48730 2/20 0.42
CSNK1G1 Q9HCP0 2/20 0.42
FGR P09769 1/20 0.42
PIM1 P11309 1/20 0.42
DYRK1A Q13627 1/20 0.42
HIPK2 Q9H2X6 1/20 0.42
PTPRC P08575 1/20 0.39
ALDH1A1 P00352 4/20 0.39
L3MBTL1 Q9Y468 3/20 0.39
NPC1 O15118 2/20 0.39
RAB9A P51151 2/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
MAPK1 P28482 2/20 0.39
CYP3A4 P08684 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13935792 0.84 ELANE (0.60) ELANECTSGMAOAMAOBADORA2A
SCHEMBL2869740 0.81 ELANE (0.66) ELANECTSGMAOBADORA2AALDH1A1
SCHEMBL11882769 0.79 ELANE (0.62) ELANECTSGMAOBADORA2AALDH1A1
SCHEMBL2127216 0.77 ELANE (0.69) ELANECTSGMAOAMAOBADORA2A
SCHEMBL11804380 0.77 ELANE (0.49) ELANECTSGMAOAMAOBADORA2A
SCHEMBL5347167 0.75 ELANE (0.53) ELANECTSGMAOAMAOBPTPRC
SCHEMBL27486561 0.73 ELANE (0.68) ELANECTSGMAOAMAOBADORA2A
SCHEMBL13935793 0.72 ELANE (0.67) ELANECTSGMAOAMAOBADORA2A
SCHEMBL398862 0.72 HTR2A (0.48) SMN1; SMN2CYP3A4POLBHPGD
SCHEMBL1399810 0.72 ELANE (0.61) ELANECTSGMAOAMAOBALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-9263571-A None JP disclosed
CN-111302961-B Method for synthesizing N-aryl/alkyl anthraquinone and derivatives thereof under catalysis of carbene metal ligand 中国科学院兰州化学物理研究所 2022-06-14 CN disclosed
CN-111302961-A Method for synthesizing N-aryl/alkyl anthraquinone and derivatives thereof under catalysis of carbene metal ligand 中国科学院兰州化学物理研究所 2020-06-19 CN disclosed
JP-H09263571-A PURIFICATION OF 1-AMINO-5-BENZOYLAMINOANTHRAQUINONE MITSUI TOATSU CHEM INC 1997-10-07 JP disclosed