Acetic Acid

Acetic Acid

SCHEMBL8931148

CC(=O)O.CCCCC=CCCCCCC(CCCC)OC(C)=O

nearest known ligand 0.52

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Known targets — ChEMBL curated mechanism

ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
F7 P08709 2/20 0.49
F3 P13726 2/20 0.49
PRKCA P17252 1/20 0.46
TERT O14746 3/20 0.45
PTPN1 P18031 3/20 0.45
MAPT P10636 2/20 0.45
BLM P54132 2/20 0.45
HSD17B10 Q99714 2/20 0.45
FABP4 P15090 2/20 0.45
PPARG P37231 2/20 0.45
PPARD Q03181 2/20 0.45
PPARA Q07869 2/20 0.45
GMNN O75496 1/20 0.45
USP2 O75604 1/20 0.45
LMNA P02545 1/20 0.45
CYP1A2 P05177 1/20 0.45
POLB P06746 1/20 0.45
CYP2C9 P11712 1/20 0.45
ALOX15 P16050 1/20 0.45
APEX1 P27695 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL834187 0.97 PRKCA (0.48) F7F3PRKCAFAAH
SCHEMBL832368 0.92 PRKCA (0.46) PRKCAMAPTFAAH
SCHEMBL833115 0.91 PRKCA (0.46) F7F3PRKCA
SCHEMBL832579 0.91 PRKCA (0.46) F7F3PRKCA
SCHEMBL833292 0.90 PRKCA (0.43) F7F3PRKCAMAPTFAAH
SCHEMBL8978211 0.89 PRKCA (0.47) F7F3PRKCA
SCHEMBL18584644 0.89 PRKCA (0.50) PRKCATERTMAPTBLMHSD17B10
SCHEMBL28923837 0.89 PRKCA (0.50) PRKCATERTMAPTBLMHSD17B10
SCHEMBL18584647 0.89 PRKCA (0.50) PRKCATERTMAPTBLMHSD17B10
SCHEMBL18584642 0.89 PRKCA (0.50) PRKCATERTMAPTBLMHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0647095-B1 INCLUSION COMPLEXES OF CYCLODEXTRIN AND THEIR USE IN SLOW RELEASE FORMULATIONS FOR ATTRACTING INSECTS NCSR DEMOKRITOS (GR) 1997-08-20 EP disclosed
US-5650160-A Inclusion complexes of cyclodextrin and their use in slow release formulations for attracting insects NCSR "DEMOKRITOS" (GR) 1997-07-22 US disclosed
EP-0647095-A1 INCLUSION COMPLEXES OF CYCLODEXTRIN AND THEIR USE IN SLOW RELEASE FORMULATIONS FOR ATTRACTING INSECTS. NCSR DEMOKRITOS (GR) 1995-04-12 EP disclosed
WO-1993025076-A1 INCLUSION COMPLEXES OF CYCLODEXTRIN AND THEIR USE IN SLOW RELEASE FORMULATIONS FOR ATTRACTING INSECTS NCSR 'DEMOKRITOS' (GR) 1993-12-23 WO disclosed