SCHEMBL8931249

SCHEMBL8931249

CCCCC[C@H]1CC[C@H](c2ccc(-c3ccc(F)cc3)cc2F)CC1

nearest known ligand 0.47

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
OPRL1 P41146 17/20 0.47
GAA P10253 1/20 0.38
MAPT P10636 1/20 0.38
GRM2 Q14416 1/20 0.38
DGAT1 O75907 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8931251 1.00 OPRL1 (0.47) OPRL1GAAMAPTGRM2DGAT1
SCHEMBL9662955 0.91 OPRL1 (0.41) OPRL1GAAMAPTDGAT1
SCHEMBL9662965 0.91 OPRL1 (0.41) OPRL1GAAMAPTDGAT1
SCHEMBL17175202 0.91 OPRL1 (0.41) OPRL1GAAMAPTDGAT1
SCHEMBL8931254 0.91 OPRL1 (0.50) OPRL1GRM2DGAT1
SCHEMBL8931253 0.91 OPRL1 (0.50) OPRL1GRM2DGAT1
SCHEMBL4822998 0.90 OPRL1 (0.40) OPRL1GAAMAPTDGAT1
SCHEMBL16377237 0.89 CYP2C9 (0.43) OPRL1GAAMAPTDGAT1
SCHEMBL17897884 0.89 CYP2C9 (0.43) OPRL1GAAMAPTDGAT1
SCHEMBL8069369 0.88 OPRL1 (0.56) OPRL1GRM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9061905-B2 Ferroelectric glass nanoparticles, liquid-crystal compositions, and electronic devices containing the nanoparticles AZIMUTH CORPORATION (US) 2015-06-23 US disclosed
US-20130329179-A1 FERROELECTRIC GLASS NANOPARTICLES, LIQUID-CRYSTAL COMPOSITIONS, AND ELECTRONIC DEVICES CONTAINING THE NANOPARTICLES AZIMUTH CORPORATION (US) 2013-12-12 US disclosed
US-5604612-A Paper white PDLC system MERCK PATENT GESELLSCAFT MIT BESCHRANKTER HAFTUNG (DE) 1997-02-18 US disclosed