SCHEMBL8931253

SCHEMBL8931253

CCC[C@H]1CC[C@H](c2ccc(-c3ccc(F)cc3)cc2F)CC1

nearest known ligand 0.50

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
OPRL1 P41146 18/20 0.50
DGAT1 O75907 1/20 0.39
GRM2 Q14416 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8931254 1.00 OPRL1 (0.50) OPRL1DGAT1GRM2
SCHEMBL8931249 0.91 OPRL1 (0.47) OPRL1DGAT1GRM2
SCHEMBL8931251 0.91 OPRL1 (0.47) OPRL1DGAT1GRM2
SCHEMBL29186355 0.90 OPRL1 (0.43) OPRL1DGAT1
SCHEMBL4650777 0.90 CYP2C9 (0.48) OPRL1DGAT1
SCHEMBL30767887 0.90 OPRL1 (0.43) OPRL1DGAT1
SCHEMBL8449030 0.88 OPRL1 (0.46) OPRL1DGAT1GRM2
SCHEMBL8449033 0.88 OPRL1 (0.46) OPRL1DGAT1GRM2
SCHEMBL17175211 0.87 CYP2C9 (0.45) OPRL1DGAT1
SCHEMBL17175201 0.87 CYP2C9 (0.45) OPRL1DGAT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9061905-B2 Ferroelectric glass nanoparticles, liquid-crystal compositions, and electronic devices containing the nanoparticles AZIMUTH CORPORATION (US) 2015-06-23 US disclosed
US-20130329179-A1 FERROELECTRIC GLASS NANOPARTICLES, LIQUID-CRYSTAL COMPOSITIONS, AND ELECTRONIC DEVICES CONTAINING THE NANOPARTICLES AZIMUTH CORPORATION (US) 2013-12-12 US disclosed
US-5604612-A Paper white PDLC system MERCK PATENT GESELLSCAFT MIT BESCHRANKTER HAFTUNG (DE) 1997-02-18 US disclosed