Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UTS2R | Q9UKP6 | 7/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.33 |
| ▸ | CDK9 | P50750 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7139908 | 0.91 | UTS2R (0.35) | UTS2RHRH1KMT2AMEN1DRD3 | |
| SCHEMBL9131002 | 0.84 | HRH1 (0.40) | HRH1KMT2AMEN1DRD3ALDH1A1 | |
| SCHEMBL7144620 | 0.84 | HRH1 (0.38) | CNR1HRH1DRD3ALDH1A1KDM4E | |
| SCHEMBL9284502 | 0.82 | HRH1 (0.43) | CNR1HRH1KMT2AMEN1DRD3 | |
| SCHEMBL7136336 | 0.82 | HRH1 (0.38) | CNR1HRH1DRD3TSHRCYP1A2 | |
| Water SCHEMBL7159274 | 0.82 | HRH1 (0.43) | CNR1HRH1KMT2AMEN1DRD3 | |
| SCHEMBL7140276 | 0.81 | HRH1 (0.34) | HRH1DRD3 | |
| SCHEMBL8931334 | 0.81 | MAPT (0.36) | HRH1KMT2AMEN1DRD3ALDH1A1 | |
| SCHEMBL7139912 | 0.81 | HRH1 (0.44) | CNR1HRH1KMT2AMEN1DRD3 | |
| Oxalic Acid SCHEMBL7134474 | 0.81 | DRD3 (0.35) | KMT2AMEN1DRD3ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5629308-A | Imidazo [1,2-A] (pyrrolo, thieno or furano) [2,3-D] azepine derivatives | JANSSEN PHARMACEUTICA N.V. (BE) | 1997-05-13 | — | — | US | disclosed |
| EP-0672047-A1 | ANTIALLERGIC IMIDAZO 1,2-a](PYRROLO, THIENO OR FURANO) 2,3-d]AZEPINE DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 1995-09-20 | — | — | EP | disclosed |
| WO-1994013680-A1 | ANTIALLERGIC IMIDAZO[1,2-a](PYRROLO, THIENO OR FURANO)[2,3-d]AZEPINE DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 1994-06-23 | — | — | WO | disclosed |