Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.79 |
| ▸ | LMNA | P02545 | 3/20 | 0.76 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | MMP12 | P39900 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | TGM2 | P21980 | 1/20 | 0.47 |
| ▸ | MMP9 | P14780 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8931470 | 1.00 | POLB (0.79) | POLBLMNAKMT2AALDH1A1CYP3A4 | |
| SCHEMBL21097453 | 1.00 | POLB (0.79) | POLBLMNAKMT2AALDH1A1CYP3A4 | |
| SCHEMBL10486898 | 0.91 | LMNA (0.72) | POLBLMNAKMT2AALDH1A1CYP3A4 | |
| SCHEMBL17267273 | 0.91 | LMNA (0.69) | POLBLMNAKMT2AALDH1A1CYP3A4 | |
| SCHEMBL15919148 | 0.91 | LMNA (0.72) | POLBLMNAKMT2AALDH1A1CYP3A4 | |
| SCHEMBL23069301 | 0.91 | LMNA (0.72) | POLBLMNAKMT2AALDH1A1CYP3A4 | |
| SCHEMBL21331976 | 0.91 | LMNA (0.69) | POLBLMNAKMT2AALDH1A1CYP3A4 | |
| SCHEMBL21574298 | 0.91 | LMNA (0.69) | POLBLMNAKMT2AALDH1A1CYP3A4 | |
| SCHEMBL10486900 | 0.91 | LMNA (0.72) | POLBLMNAKMT2AALDH1A1CYP3A4 | |
| SCHEMBL17278377 | 0.91 | LMNA (0.69) | POLBLMNAKMT2AALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5654412-A | CONVERGENT SYNTHESIS VIA TWO DISACCHARIDE SUBCOMPONENTS; SIMPLIFICATION, HIGH YIELD | GLYCOMED INCORPORATED (US) | 1997-08-05 | — | — | US | disclosed |