⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10768997 | 0.76 | — | — | |
| SCHEMBL4802559 | 0.74 | — | — | |
| SCHEMBL11805955 | 0.70 | — | — | |
| SCHEMBL6760286 | 0.69 | ALDH1A1 (0.32) | — | |
| SCHEMBL4806395 | 0.68 | MGAM (0.44) | — | |
| SCHEMBL9809649 | 0.67 | — | — | |
| SCHEMBL11233487 | 0.67 | — | — | |
| SCHEMBL3715370 | 0.67 | — | — | |
| SCHEMBL16022795 | 0.67 | — | — | |
| SCHEMBL28399014 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0546306-B1 | 5-(2-Chloroalkyl)-4-methylthiazoles, their preparation and their use, and intermediates for their preparation | ASTRA AB (SE) | 1997-04-16 | — | — | EP | claimed |
| EP-0546306-A1 | 5-(2-Chloroalkyl)-4-methylthiazoles, their preparation and their use, and intermediates for their preparation | Astra Aktiebolag (SE) | 1993-06-16 | — | — | EP | claimed |
| EP-0546306-B1 | 5-(2-Chloroalkyl)-4-methylthiazoles, their preparation and their use, and intermediates for their preparation | ASTRA AB (SE) | 1997-04-16 | — | — | EP | disclosed |
| EP-0546306-A1 | 5-(2-Chloroalkyl)-4-methylthiazoles, their preparation and their use, and intermediates for their preparation | Astra Aktiebolag (SE) | 1993-06-16 | — | — | EP | disclosed |