Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.47 |
| ▸ | PER2 | O15055 | 4/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.40 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | APEX1 | P27695 | 2/20 | 0.40 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12228961 | 0.80 | PIK3CD (0.53) | PIK3CDPER2TSHRCHRM2CHRM5 | |
| SCHEMBL18861324 | 0.77 | PIK3CD (0.43) | PIK3CDPER2TSHRCHRM2CHRM5 | |
| SCHEMBL25173747 | 0.77 | PER2 (0.54) | PIK3CDPER2TSHRCHRM2CHRM5 | |
| SCHEMBL7619112 | 0.77 | PIK3CD (0.50) | PIK3CDPER2TSHRCHRM2CHRM5 | |
| SCHEMBL18681180 | 0.77 | PIK3CD (0.50) | PIK3CDPER2TSHRCHRM2CHRM5 | |
| SCHEMBL23484442 | 0.75 | PER2 (0.45) | PIK3CDPER2TSHRCHRM2CHRM5 | |
| SCHEMBL7623400 | 0.75 | PIK3CD (0.41) | PIK3CDPER2TSHRCHRM2CHRM5 | |
| SCHEMBL12032481 | 0.75 | PER2 (0.50) | PIK3CDPER2TSHRCHRM2CHRM5 | |
| SCHEMBL341356 | 0.74 | PIK3CD (0.47) | PIK3CDPER2TSHRCHRM2CHRM5 | |
| SCHEMBL21290167 | 0.74 | PIK3CD (0.40) | PIK3CDPER2TSHRCHRM2CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0812323-A1 | DERIVATIVES OF 3-PYRROLIDYLIDENE-2-ONE-CEPHALOSPORINES | F. HOFFMANN-LA ROCHE AG (CH) | 1997-12-17 | — | — | EP | disclosed |
| WO-1996026943-A1 | DERIVATIVES OF 3-PYRROLIDYLIDENE-2-ONE-CEPHALOSPORINES | F.HOFFMANN-LA ROCHE AG (CH) | 1996-09-06 | — | — | WO | disclosed |