Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 4/20 | 0.39 |
| ▸ | AGTR2 | P50052 | 4/20 | 0.39 |
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.39 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8931904 | 0.91 | AGTR1 (0.41) | AGTR1AGTR2LTB4R2 | |
| SCHEMBL8931850 | 0.90 | AGTR1 (0.41) | AGTR1AGTR2LTB4R2 | |
| SCHEMBL8931810 | 0.89 | AGTR1 (0.41) | AGTR1AGTR2LTB4R2 | |
| SCHEMBL8931961 | 0.87 | AGTR1 (0.39) | AGTR1AGTR2LTB4R2ALDH1A1 | |
| SCHEMBL8931852 | 0.77 | LTB4R2 (0.39) | AGTR1AGTR2LTB4R2 | |
| SCHEMBL8931987 | 0.73 | LTB4R2 (0.41) | AGTR1AGTR2LTB4R2 | |
| SCHEMBL8931954 | 0.73 | AGTR1 (0.42) | AGTR1AGTR2 | |
| SCHEMBL8931792 | 0.72 | AGTR1 (0.41) | AGTR1AGTR2LTB4R2 | |
| SCHEMBL8931833 | 0.72 | AGTR1 (0.40) | AGTR1AGTR2 | |
| SCHEMBL8931818 | 0.72 | AGTR1 (0.41) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5693633-A | Angiotensin II antagonists | ELI LILLY AND COMPANY (US) | 1997-12-02 | — | — | US | disclosed |