Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 4/20 | 0.43 |
| ▸ | EHMT2 | Q96KQ7 | 5/20 | 0.43 |
| ▸ | SUV39H1 | O43463 | 2/20 | 0.43 |
| ▸ | ACHE | P22303 | 8/20 | 0.43 |
| ▸ | BCHE | P06276 | 5/20 | 0.43 |
| ▸ | NSD2 | O96028 | 1/20 | 0.39 |
| ▸ | EP300 | Q09472 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.39 |
| ▸ | NSD1 | Q96L73 | 1/20 | 0.39 |
| ▸ | NSD3 | Q9BZ95 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Chimonanthine SCHEMBL20927442 | 1.00 | TACR1 (0.43) | TACR1EHMT2SUV39H1ACHEBCHE | |
| Chimonanthine SCHEMBL29515267 | 1.00 | TACR1 (0.43) | TACR1EHMT2SUV39H1ACHEBCHE | |
| Calycanthine SCHEMBL29878816 | 1.00 | TACR1 (0.43) | TACR1EHMT2SUV39H1ACHEBCHE | |
| Chimonanthine SCHEMBL29779948 | 1.00 | TACR1 (0.43) | TACR1EHMT2SUV39H1ACHEBCHE | |
| Calycanthine SCHEMBL29779950 | 1.00 | TACR1 (0.43) | TACR1EHMT2SUV39H1ACHEBCHE | |
| SCHEMBL30555832 | 0.87 | TACR1 (0.39) | TACR1EHMT2SUV39H1ACHEBCHE | |
| SCHEMBL1006038 | 0.85 | TACR1 (0.36) | TACR1EHMT2SUV39H1ACHEBCHE | |
| SCHEMBL20927487 | 0.85 | TACR1 (0.36) | TACR1EHMT2SUV39H1ACHEBCHE | |
| SCHEMBL20927482 | 0.85 | TACR1 (0.36) | TACR1EHMT2SUV39H1ACHEBCHE | |
| SCHEMBL19655969 | 0.85 | TACR1 (0.36) | TACR1EHMT2SUV39H1ACHEBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 116 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110840885-B | Anti-nasopharyngeal cancer application of vegetarian calyxin | 北京麦思迪国际医药科技有限公司 | 2022-12-06 | — | — | CN | claimed |
| CN-110680838-B | Application of vegetarian calycanthine in resisting prostate cancer | 海门茂发美术图案设计有限公司 | 2021-10-01 | — | — | CN | claimed |
| CN-111012806-B | New application of vegetarian calycanthine in resisting breast cancer | 海门茂发美术图案设计有限公司 | 2021-10-01 | — | — | CN | claimed |
| CN-111012806-A | New application of vegetarian calycanthine in resisting breast cancer | 南京凡亦达生物科技有限公司 | 2020-04-17 | — | — | CN | claimed |
| CN-110840885-A | Anti-nasopharyngeal cancer application of vegetarian calyxin | 南京凡亦达生物科技有限公司 | 2020-02-28 | — | — | CN | claimed |
| CN-110680838-A | Application of vegetarian calycanthine in resisting prostate cancer | 南京凡亦达生物科技有限公司 | 2020-01-14 | — | — | CN | claimed |
| CN-109535157-A | A kind of half calycanthine analog, its preparation method and use | 江苏科技大学 | 2019-03-29 | — | — | CN | claimed |
| US-20170364630-A1 | IDENTIFICATION OF CELLULAR ANTIMICROBIAL DRUG TABLETS THROUGH INTERACTOME ANALYSIS | VANDERBILT UNIVERSITY | 2017-12-21 | — | — | US | claimed |
| WO-2016090362-A1 | IDENTIFICATION OF CELLULAR ANTIMICROBIAL DRUG TARGETS THROUGH INTERACTOME ANALYSIS | VANDERBILT UNIVERSITY (US) | 2016-06-09 | — | — | WO | claimed |
| EP-2665739-A1 | METHODS AND COMPOSITIONS RELATED TO SYNERGISTIC RESPONSES TO ONCOGENIC MUTATIONS | THE UNIVERSITY OF ROCHESTER (US) | 2013-11-27 | — | — | EP | claimed |
| WO-2012100248-A1 | METHODS AND COMPOSITIONS RELATED TO SYNERGISTIC RESPONSES TO ONCOGENIC MUTATIONS | THE UNIVERSITY OF ROCHESTER (US) | 2012-07-26 | — | — | WO | claimed |
| US-20120114670-A1 | METHODS AND COMPOSITIONS RELATED TO SYNERGISTIC RESPONSES TO ONCOGENIC MUTATIONS | UNIVERSITY OF ROCHESTER (US) | 2012-05-10 | — | — | US | claimed |
| US-20120082659-A1 | Methods And Compositions Related To Synergistic Responses To Oncogenic Mutations | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2012-04-05 | — | — | US | claimed |
| US-20100285001-A1 | Method and Compositions Related to Synergistic Responses to Oncogenic Mutations | UNIVERSITY OF ROCHESTER (US) | 2010-11-11 | — | — | US | claimed |
| EP-2188630-A2 | METHODS AND COMPOSITIONS RELATED TO SYNERGISTIC RESPONSES TO ONCOGENIC MUTATIONS | THE UNIVERSITY OF ROCHESTER (US) | 2010-05-26 | — | — | EP | claimed |
| WO-2009045443-A2 | METHODS AND COMPOSITIONS RELATED TO SYNERGISTIC RESPONSES TO ONCOGENIC MUTATIONS | THE UNIVERSITY OF ROCHESTER (US) | 2009-04-09 | — | — | WO | claimed |
| EP-2001877-A1 | METHOD FOR EXTRACTING TARGET ALKALOID USING AN IONIC LIQUID AS EXTRACTING SOLVENT | Bioniqs Limited (GB) | 2008-12-17 | — | — | EP | claimed |
| WO-2007110637-A1 | METHOD FOR EXTRACTING TARGET ALKALOID USING AN IONIC LIQUID AS EXTRACTING SOLVENT | BIONIQS LIMITED (GB) | 2007-10-04 | — | — | WO | claimed |
| US-20240052418-A1 | METHOD FOR PREDICTING A SUBJECT'S RESPONSE TO SLC MODULATOR THERAPY | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2024-02-15 | — | — | US | disclosed |
| CN-1040206-A | Prevent to form the method for polymer scale formation | SHINETSU CHEMICAL CO (JP) | 1990-03-07 | — | — | CN | disclosed |