Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMP | P19971 | 1/20 | 0.39 |
| ▸ | TK2 | O00142 | 11/20 | 0.38 |
| ▸ | TK1 | P04183 | 7/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8932074 | 0.89 | TK2 (0.35) | TYMPTK2TK1 | |
| SCHEMBL8932073 | 0.84 | TK1 (0.34) | TK2TK1 | |
| SCHEMBL30657784 | 0.83 | TYMP (0.40) | TYMPTK2TK1 | |
| SCHEMBL6830774 | 0.81 | TYMP (0.42) | TYMPTK2TK1 | |
| SCHEMBL8332688 | 0.80 | TK1 (0.37) | TYMPTK1 | |
| SCHEMBL6830082 | 0.78 | TK1 (0.39) | TK2TK1 | |
| SCHEMBL9614228 | 0.77 | TK2 (0.37) | TYMPTK2TK1 | |
| SCHEMBL6827522 | 0.76 | TK1 (0.38) | TK2TK1 | |
| SCHEMBL6830069 | 0.76 | TK1 (0.38) | TK2TK1 | |
| SCHEMBL8931958 | 0.76 | TYMP (0.38) | TYMPTK2TK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5681940-A | CONTAIN TETRAHYDROTHIOPHENE OR PYROLIDINE RINGS | ICN PHARMACEUTICALS (US) | 1997-10-28 | — | — | US | disclosed |