Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | EDNRA | P25101 | 1/20 | 0.56 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.55 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.55 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.55 |
| ▸ | FABP7 | O15540 | 6/20 | 0.55 |
| ▸ | FABP5 | Q01469 | 5/20 | 0.55 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.54 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.54 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.54 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.54 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.54 |
| ▸ | FABP3 | P05413 | 3/20 | 0.53 |
| ▸ | P4HB | P07237 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8643008 | 0.97 | POLB (0.64) | POLBALDH1A1GAAEDNRAGRM1 | |
| SCHEMBL1029251 | 0.97 | POLB (0.64) | POLBALDH1A1GAAEDNRAGRM1 | |
| SCHEMBL20598122 | 0.92 | POLB (0.70) | POLBALDH1A1GAAEDNRAGRM1 | |
| SCHEMBL21120223 | 0.92 | POLB (0.70) | POLBALDH1A1GAAEDNRAGRM1 | |
| SCHEMBL3482620 | 0.92 | POLB (0.70) | POLBALDH1A1GAAEDNRAGRM1 | |
| SCHEMBL4560501 | 0.92 | POLB (0.70) | POLBALDH1A1GAAEDNRAGRM1 | |
| SCHEMBL3482659 | 0.92 | HDAC4 (0.61) | POLBALDH1A1GAAEDNRAGRM1 | |
| SCHEMBL20614651 | 0.92 | POLB (0.70) | POLBALDH1A1GAAEDNRAGRM1 | |
| SCHEMBL18674152 | 0.92 | POLB (0.70) | POLBALDH1A1GAAEDNRAGRM1 | |
| SCHEMBL15590565 | 0.92 | POLB (0.70) | POLBALDH1A1GAAEDNRAGRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0573848-B1 | Bile-acid derivatives, a process for their production and their use as medicines | HOECHST AG (DE) | 1997-12-03 | — | — | EP | disclosed |
| US-5428182-A | Hypolipidemic agents | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-06-27 | — | — | US | disclosed |
| EP-0573848-A2 | Bile-acid derivatives, a process for their production and their use as medicines | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-12-15 | — | — | EP | disclosed |