⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8274102 | 0.75 | — | — | |
| SCHEMBL107617 | 0.75 | — | — | |
| SCHEMBL28209249 | 0.75 | CA5A (0.35) | — | |
| Hydrochloric Acid SCHEMBL27484357 | 0.73 | — | — | |
| SCHEMBL7058126 | 0.73 | CA5A (0.33) | — | |
| SCHEMBL27572583 | 0.73 | — | — | |
| Nitric Acid SCHEMBL6263829 | 0.71 | CA5A (0.47) | — | |
| SCHEMBL28662297 | 0.71 | — | — | |
| SCHEMBL940993 | 0.71 | — | — | |
| SCHEMBL940991 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170233307-A1 | SYSTEMS FOR PRODUCING DEMN EUTECTIC, AND RELATED METHODS OF FORMING AN ENERGETIC COMPOSITION | NORTHROP GRUMMAN SYSTEMS CORPORATION | 2017-08-17 | — | — | US | disclosed |
| US-8188133-B2 | Imidazole derivatives, preparation and user thereof as medicine | IPSEN PHARMA S.A.S. (FR) | 2012-05-29 | — | — | US | disclosed |
| US-7973035-B2 | Inhibitors of C-FMS kinase | JANSSEN PHARMACEUTICA, N.V. (BE) | 2011-07-05 | — | — | US | disclosed |
| US-20090186930-A1 | NOVEL IMIDAZOLE DERIVATIVES, PREPARATION AND USER THEREOF AS MEDICINE | SOCIETE DE CONSEILS DE RECHERCHES ET D' APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 2009-07-23 | — | — | US | disclosed |
| US-20080275031-A1 | 4-Cyano-1H-imidazole-2-carboxylic acid [2-cyclohex-1-enyl-4-(2,6-dioxo-piperidin-4-yl)-phenyl]-amide; tyrosine kinase inhibitor; autoimmune diseases, antiinflammatory, anticarcinogenic agent | ILLIG CARL R | 2008-11-06 | — | — | US | disclosed |