Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29300034 | 0.90 | CES1 (0.38) | CES1PLA2G2CHSD17B10MEN1THRB | |
| SCHEMBL125933 | 0.90 | — | — | |
| SCHEMBL127742 | 0.85 | CES1 (0.52) | CES1PLA2G2CTSHRCES2HSD17B10 | |
| SCHEMBL9076724 | 0.84 | CES1 (0.38) | CES1PLA2G2CHTTEPHX2 | |
| SCHEMBL128551 | 0.83 | CES1 (0.61) | CES1PLA2G2CTSHRCES2HSD17B10 | |
| Fluoride SCHEMBL27418704 | 0.83 | CES1 (0.50) | CES1PLA2G2CTSHRCES2HSD17B10 | |
| SCHEMBL11995953 | 0.83 | CES1 (0.41) | CES1PLA2G2CTSHRCES2HSD17B10 | |
| SCHEMBL17920759 | 0.81 | TSHR (0.36) | CES1TSHRCES2HSD17B10MEN1 | |
| SCHEMBL128963 | 0.81 | CES1 (0.64) | CES1PLA2G2CTSHRCES2HSD17B10 | |
| SCHEMBL19043522 | 0.81 | CES1 (0.64) | CES1PLA2G2CTSHRCES2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8187732-B2 | Media lubricant for high temperature application | SEAGATE TECHNOLOGY LLC (US) | 2012-05-29 | — | — | US | disclosed |
| US-20110117386-A1 | MEDIA LUBRICANT FOR HIGH TEMPERATURE APPLICATION | SEAGATE TECHNOLOGY LLC (US) | 2011-05-19 | — | — | US | disclosed |