Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20284326 | 0.77 | TDP1 (0.53) | TDP1GAALMNAALDH1A1POLB | |
| SCHEMBL17522580 | 0.68 | — | — | |
| SCHEMBL1187218 | 0.68 | SMN1; SMN2 (0.36) | TDP1GAALMNAMAPTPOLB | |
| SCHEMBL17291125 | 0.68 | PDCD1 (0.48) | GAAKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL17525125 | 0.67 | GAA (0.50) | TDP1GAATHRBRECQLKDM4E | |
| SCHEMBL2595479 | 0.67 | TDP1 (0.47) | TDP1GAALMNAALDH1A1MAPT | |
| SCHEMBL3338521 | 0.65 | GAA (0.44) | GAATHRBRECQLKDM4EL3MBTL1 | |
| SCHEMBL10497099 | 0.65 | LMNA (0.44) | GAATHRBRECQLKDM4EL3MBTL1 | |
| SCHEMBL12285505 | 0.63 | — | — | |
| SCHEMBL15690207 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5536701-A | 3-pyrazolyloxypyridazines, herbicidal compositions and uses thereof | MONSANTO COMPANY (US) | 1996-07-16 | — | — | US | disclosed |