Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | TGFBR1 | P36897 | 5/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.30 |
| ▸ | FLT3 | P36888 | 1/20 | 0.30 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.30 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.30 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8478285 | 0.84 | ADORA2A (0.47) | KMT2ATGFBR1ADORA2AADORA1ALDH1A1 | |
| SCHEMBL8932297 | 0.83 | KMT2A (0.48) | KMT2ATGFBR1ADORA2AADORA1ALDH1A1 | |
| SCHEMBL8932244 | 0.83 | KMT2A (0.48) | KMT2ATGFBR1ADORA2AADORA1ALDH1A1 | |
| SCHEMBL8932255 | 0.82 | KMT2A (0.47) | KMT2ATGFBR1ADORA2AADORA1ALDH1A1 | |
| SCHEMBL8932283 | 0.82 | KMT2A (0.47) | KMT2ATGFBR1ADORA2AADORA1ALDH1A1 | |
| SCHEMBL8932234 | 0.81 | KMT2A (0.49) | KMT2ATGFBR1ADORA2AADORA1ALDH1A1 | |
| SCHEMBL8932303 | 0.80 | KMT2A (0.45) | KMT2ATGFBR1ADORA2AADORA1ALDH1A1 | |
| SCHEMBL8932278 | 0.79 | KMT2A (0.44) | KMT2ATGFBR1ADORA2AADORA1ALDH1A1 | |
| SCHEMBL8932322 | 0.79 | KMT2A (0.44) | KMT2ATGFBR1ADORA2AADORA1ALDH1A1 | |
| SCHEMBL8932272 | 0.79 | KMT2A (0.44) | KMT2ATGFBR1ADORA2AADORA1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5536701-A | 3-pyrazolyloxypyridazines, herbicidal compositions and uses thereof | MONSANTO COMPANY (US) | 1996-07-16 | — | — | US | disclosed |