Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 7/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | PRKDC | P78527 | 1/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8475741 | 0.84 | ADORA2A (0.46) | KMT2AADORA2AADORA1TGFBR1ALDH1A1 | |
| SCHEMBL8932244 | 0.82 | KMT2A (0.48) | KMT2AADORA2AADORA1TGFBR1ALDH1A1 | |
| SCHEMBL8932297 | 0.82 | KMT2A (0.48) | KMT2AADORA2AADORA1TGFBR1ALDH1A1 | |
| SCHEMBL8932255 | 0.81 | KMT2A (0.47) | KMT2AADORA2AADORA1TGFBR1ALDH1A1 | |
| SCHEMBL8932283 | 0.81 | KMT2A (0.47) | KMT2AADORA2AADORA1TGFBR1ALDH1A1 | |
| SCHEMBL8932234 | 0.80 | KMT2A (0.49) | KMT2AADORA2AADORA1TGFBR1ALDH1A1 | |
| SCHEMBL7252609 | 0.79 | KMT2A (0.46) | KMT2AADORA2AADORA1TGFBR1ALDH1A1 | |
| SCHEMBL5221402 | 0.79 | KMT2A (0.47) | KMT2AADORA2AADORA1TGFBR1ALDH1A1 | |
| SCHEMBL8932289 | 0.79 | KMT2A (0.45) | KMT2AADORA2AADORA1TGFBR1ALDH1A1 | |
| SCHEMBL8932303 | 0.79 | KMT2A (0.45) | KMT2AADORA2AADORA1TGFBR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5536701-A | 3-pyrazolyloxypyridazines, herbicidal compositions and uses thereof | MONSANTO COMPANY (US) | 1996-07-16 | — | — | US | disclosed |