Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.67 |
| ▸ | MEN1 | O00255 | 3/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.66 |
| ▸ | HTT | P42858 | 2/20 | 0.66 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.66 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.66 |
| ▸ | TP53 | P04637 | 1/20 | 0.66 |
| ▸ | POLB | P06746 | 4/20 | 0.64 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5707911 | 0.95 | MAPT (0.63) | MAPTKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL1387486 | 0.85 | MAPT (0.74) | MAPTKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL6602614 | 0.84 | MAPT (0.67) | MAPTKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL3012718 | 0.83 | AKR1C3 (0.67) | MAPTKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL13181103 | 0.83 | MAPT (0.70) | MAPTKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL27783156 | 0.83 | AKR1C3 (0.85) | MAPTKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL31406888 | 0.82 | MAPT (0.64) | MAPTKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL3092444 | 0.82 | KMT2A (0.67) | MAPTKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL13153237 | 0.82 | MAPT (0.68) | MAPTKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL1393155 | 0.81 | AKR1C3 (0.68) | MAPTKMT2AMEN1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996026936-A1 | NOVEL CYCLIC AMINO-INDOLE PIPERAZINE DERIVATIVES, PREPARATION PROCESS AND UTILIZATION AS MEDICAMENTS | PIERRE FABRE MEDICAMENT (FR) | 1996-09-06 | — | — | WO | disclosed |