Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 2/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.33 |
| ▸ | PLAU | P00749 | 2/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.30 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2780927 | 0.72 | PLAU (0.54) | ADRA2AADRA2BADRA2CPLAUHSP90AA1 | |
| SCHEMBL1855296 | 0.67 | — | — | |
| SCHEMBL1352941 | 0.65 | HSP90AA1 (0.39) | PLAUHDAC8HSP90AA1 | |
| SCHEMBL2469365 | 0.65 | HDAC8 (0.39) | HDAC8HSP90AA1 | |
| SCHEMBL29919450 | 0.65 | HDAC8 (0.39) | HDAC8HSP90AA1 | |
| SCHEMBL1029555 | 0.63 | — | — | |
| SCHEMBL21373267 | 0.61 | NOS3 (0.34) | — | |
| SCHEMBL21373268 | 0.61 | NOS3 (0.34) | — | |
| SCHEMBL1855295 | 0.61 | — | — | |
| SCHEMBL1388023 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996026939-A1 | CARBAPENEM COMPOUNDS, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-09-06 | — | — | WO | disclosed |