SCHEMBL8932457

SCHEMBL8932457

COCCSC1=NCC(SC(OC)c2ccccc2)CN1

nearest known ligand 0.32

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
MAP2K7 O14733 1/20 0.32
CDC25A P30304 1/20 0.32
CDC25B P30305 1/20 0.32
MAN2A1 Q16706 1/20 0.31
MAN1B1 Q9UKM7 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8932505 0.75 CHRM2 (0.36)
SCHEMBL8932455 0.72 ALDH1A1 (0.37)
SCHEMBL8932469 0.61 TACR1 (0.35)
SCHEMBL1025612 0.59 ALDH1A1 (0.64) MAP2K7CDC25ACDC25B
SCHEMBL5503227 0.57 KMT2A (0.38)
SCHEMBL31499299 0.57 KMT2A (0.40)
SCHEMBL1782470 0.57 KMT2A (0.40)
SCHEMBL6651178 0.57 KMT2A (0.40)
SCHEMBL10992763 0.56 ALDH1A1 (0.51)
SCHEMBL14734012 0.55 HSD17B10 (0.53) MAP2K7CDC25ACDC25B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1996026939-A1 CARBAPENEM COMPOUNDS, THEIR PRODUCTION AND USE TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1996-09-06 WO disclosed