SCHEMBL8932474

SCHEMBL8932474

CSC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.38

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.38
THRB P10828 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9430621 1.00 LMNA (0.38) LMNATHRB
SCHEMBL9903645 1.00 LMNA (0.38) LMNATHRB
SCHEMBL9903130 1.00 LMNA (0.38) LMNATHRB
SCHEMBL776072 0.97 LMNA (0.33) LMNA
SCHEMBL576112 0.87
SCHEMBL30421649 0.73 LMNA (0.42) LMNATHRB
SCHEMBL8105478 0.73 LMNA (0.42) LMNATHRB
SCHEMBL1978019 0.73 LMNA (0.42) LMNATHRB
SCHEMBL775557 0.73 LMNA (0.30) LMNA
SCHEMBL777830 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1996026185-A1 REAGENT, COMPOUND AND METHOD FOR NUCLEOPHILE PERFLUOROALKYLATION, AND RESULTING DERIVATIVES RHONE-POULENC AGROCHIMIE (FR) 1996-08-29 WO disclosed