SCHEMBL89327

SCHEMBL89327

O=C1C=CCN1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL27731613 0.97
Methane SCHEMBL595114 0.97
SCHEMBL29053757 0.89 GSK3A (0.55)
SCHEMBL7447684 0.80
SCHEMBL1035336 0.72
SCHEMBL279748 0.71
5,6-Dihydro-2(1H)-Pyridinone SCHEMBL49488 0.71
SCHEMBL586833 0.69
5,6-Dihydro-2(1H)-Pyridinone SCHEMBL31482438 0.69
5,6-Dihydro-2(1H)-Pyridinone SCHEMBL9464948 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1462 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024153155-A1 DOUBLE-HETEROCYCLIC WRN INHIBITOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF 成都微芯药业有限公司 2024-07-25 WO claimed
CN-113767092-B Di-heterocyclic carbonyl substituted dihydropyrazoles, their preparation and their use in medicine 劲方医药科技(上海)有限公司 2024-07-16 CN claimed
EP-3762339-B1 METHODS TO REDUCE N-HETEROCYCLES BL TECHNOLOGIES INC (US) 2024-06-12 EP claimed
CN-115551867-B Fused tricyclic compounds, pharmaceutical compositions and uses thereof 劲方医药科技(上海)有限公司 2024-02-20 CN claimed
CN-111801301-B Methods and compositions for reducing azole and AOX corrosion inhibitors BL 科技公司 2023-11-24 CN claimed
US-11760666-B2 Methods and compositions to reduce azoles and AOX corrosion inhibitors BL TECHNOLOGIES, INC. (US) 2023-09-19 US claimed
US-20230203060-A1 FUSED TRICYCLIC COMPOUND, PHARMACEUTICAL COMPOSITION THEREOF, AND USE THEREOF GENFLEET THERAPEUTICS (SHANGHAI) INC. (CN) 2023-06-29 US claimed
US-20230180758-A1 SUBSTITUTED PYRROLINE-2-ONES AND THEIR USE AS HERBICIDES BAYER AKTIENGESELLSCHAFT (DE) 2023-06-15 US claimed
WO-2023079538-A1 A NOVEL PROCESS FOR PREPARATION OF 5-HYDROXY-5-ARYL-PYRROL-2-ONES AND THEIR INTERMEDIATES PNB VESPER LIFE SCIENCE PVT LIMITED (IN) 2023-05-11 WO claimed
CN-116041345-A Preparation method of compound with optical activity and hydantoin skeleton 温州大学 2023-05-02 CN claimed
US-5312929-A 2-oxo-3-pyrroline derivatives, process for their production and herbicidal composition KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 1994-05-17 US claimed
US-5283165-A Solid particular filter dye dispersion in photography EASTMAN KODAK COMPANY (US) 1994-02-01 US claimed
EP-0557691-A1 4-Methyl-3-phenyl-2-oxo-3-pyrroline derivatives, process for their preparation and herbicidal compositions KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 1993-09-01 EP claimed
US-5218021-A Improved foam stability, extinguishing ability and burnback resistance CIBA-GEIGY CORPORATION (US) 1993-06-08 US claimed
EP-0524138-A1 Compositions for polar solvent fire fighting containing perfluoroalkyl terminated co-oligomer concentrates and polysaccharides CIBA-GEIGY AG (CH) 1993-01-20 EP claimed
EP-0483667-A2 Cyclic imino derivatives, process for their preparation and drugs containing them Dr. Karl Thomae GmbH (DE) 1992-05-06 EP claimed
US-5008402-A Reacting a 3-pyrrolin-2-one with an aldehyde or ketone; hydrogenating LONZA LTD. (CH) 1991-04-16 US claimed
EP-0358128-A2 Process for the preparation of 5-alkyltetramic acids LONZA AG (CH) 1990-03-14 EP claimed
US-4443616-A Production of 3-pyrrolin-2-ones THE PURDUE FREDERICK COMPANY (US) 1984-04-17 US claimed
EP-0005143-B1 1-BENZOYL-2-PYRROLIDINONE DERIVATIVE, PROCESSES FOR ITS PREPARATION AND MEDICAMENTS CONTAINING IT F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) 1982-07-14 EP claimed