SCHEMBL279748

SCHEMBL279748

O=C1C=CCNN1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3822641 0.73
SCHEMBL89327 0.71
Methane SCHEMBL595114 0.69
Hydrochloric Acid SCHEMBL27731613 0.69
SCHEMBL29053757 0.63 GSK3A (0.55)
SCHEMBL7199064 0.59 GSK3A (0.59)
SCHEMBL11816980 0.59 GSK3A (0.41)
SCHEMBL723377 0.56
SCHEMBL1077045 0.56
SCHEMBL1404159 0.56

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113939295-B Pyridazinones and methods of use thereof 金翅雀生物公司 2025-05-16 CN disclosed
WO-2018133793-A1 BLOOD COAGULATION FACTOR XIA INHIBITOR AND USES THEREOF 广东东阳光药业有限公司 2018-07-26 WO disclosed
US-9527828-B2 Method for expanding hematopoietic stem cells using heterocyclic compound NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2016-12-27 US disclosed
US-9328085-B2 Heterocyclic compounds and expansion agents for hematopoietic stem cells NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2016-05-03 US disclosed
US-8889732-B2 Fused heterocyclic compounds and thrombopoietin receptor activators NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2014-11-18 US disclosed
US-20140227780-A1 METHOD FOR PRODUCING MEGAKARYOCYTES AND/OR PLATELETS FROM PLURIPOTENT STEM CELLS NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2014-08-14 US disclosed
US-8552031-B2 3-ethylidenehydrazino substituted heterocyclic compounds as thrombopoietin receptor activators NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2013-10-08 US disclosed
US-20130245255-A1 HETEROCYCLIC COMPOUNDS AND EXPANSION AGENTS FOR HEMATOPOIETIC STEM CELLS NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2013-09-19 US disclosed
US-8440666-B2 Pyridazinone compounds and P2X7 receptor inhibitors NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2013-05-14 US disclosed
US-8440666-B2 Pyridazinone compounds and P2X7 receptor inhibitors NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2013-05-14 US disclosed
US-20090118500-A1 THIOPHENE COMPOUNDS AND THROMBOPOIETIN RECEPTOR ACTIVATORS NISSAN CHEMICAL INDUSTRIES, LTD (JP) 2009-05-07 US disclosed
US-20090118500-A1 THIOPHENE COMPOUNDS AND THROMBOPOIETIN RECEPTOR ACTIVATORS NISSAN CHEMICAL INDUSTRIES, LTD (JP) 2009-05-07 US disclosed
WO-2009057827-A1 PYRIDAZINONE DERIVATIVES AND USE THEREOF AS P2X7 RECEPTOR INHIBITORS NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2009-05-07 WO disclosed
US-20090023939-A1 ALPHA-SUBSTITUTED VINYLTIN COMPOUND NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2009-01-22 US disclosed
CN-100399192-C Silver halide colour photographic photo-sensitive material FUJI PHOTO FILM CO LTD (JP) 2008-07-02 CN disclosed
CN-1245660-C Color coupler for forming dye, silver halide photosensitive material and azomethine dyes compounds FUJI PHOTO FILM CO LTD (JP) 2006-03-15 CN disclosed
US-20050187138-A1 Peptide beta-strand mimics based on pyridinones, pyrazinones, pyridazinones, and triazinones THE REGENTS OF THE UNIVERSITY OF CALIFORNIA, A CALIFORNIA CORPORATION (US) 2005-08-25 US disclosed
CN-1423164-A Silver halide colour photographic photo-sensitive material FUJI PHOTO FILM CO LTD (JP) 2003-06-11 CN disclosed
CN-1387087-A Color coupler for forming dye, silver halide photosensitive material and azomethine dyes compounds FUJI PHOTO FILM CO LTD (JP) 2002-12-25 CN disclosed
CN-1038249-C Dihydropyridazinones, pyridazinones and related compounds as fungicides ROHM & HAAS (US) 1998-05-06 CN disclosed