Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP2 | Q9UGN5 | 4/20 | 0.41 |
| ▸ | PARP1 | P09874 | 4/20 | 0.41 |
| ▸ | SCN1A | P35498 | 9/20 | 0.40 |
| ▸ | SCN5A | Q14524 | 9/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 9/20 | 0.40 |
| ▸ | MTR | Q99707 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8658094 | 0.86 | MTR (0.45) | PARP2PARP1SCN1ASCN5ASCN9A | |
| SCHEMBL6186340 | 0.81 | MTR (0.43) | PARP2SCN1ASCN5ASCN9AMTR | |
| SCHEMBL6190749 | 0.81 | MTR (0.43) | PARP2SCN1ASCN5ASCN9AMTR | |
| SCHEMBL6186350 | 0.81 | MTR (0.43) | PARP2SCN1ASCN5ASCN9AMTR | |
| SCHEMBL8191068 | 0.73 | MTR (0.48) | SCN1ASCN5ASCN9AMTR | |
| SCHEMBL8191064 | 0.73 | MTR (0.48) | SCN1ASCN5ASCN9AMTR | |
| SCHEMBL6188446 | 0.72 | MTR (0.49) | PARP2SCN1ASCN5ASCN9AMTR | |
| SCHEMBL8484929 | 0.72 | MTR (0.39) | PARP2PARP1SCN1ASCN5ASCN9A | |
| SCHEMBL8484926 | 0.72 | NPY1R (0.40) | PARP2PARP1SCN1ASCN5ASCN9A | |
| SCHEMBL8199450 | 0.72 | MTR (0.47) | SCN1ASCN5ASCN9AMTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996026205-A1 | INHIBITORS OF MICROSOMAL TRIGLYCERIDE TRANSFER PROTEIN AND METHOD | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-08-29 | — | — | WO | disclosed |