SCHEMBL8933284

SCHEMBL8933284

N=C(N)c1ccc(C(N)=O)cn1.O=C(O)C1CN1CC(=O)N1CCC[C@]1(C(=O)O)C1CCCCC1

nearest known ligand 0.33

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
OPRK1 P41145 3/20 0.33
OPRM1 P35372 2/20 0.33
ITGB3 P05106 1/20 0.32
ITGA2B P08514 1/20 0.32
KCNH2 Q12809 1/20 0.30
F2 P00734 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6476401 0.85 ITGB3 (0.36) OPRK1OPRM1ITGB3ITGA2BKCNH2
SCHEMBL6487745 0.84 ITGB3 (0.36) OPRK1OPRM1ITGB3ITGA2BKCNH2
SCHEMBL6477039 0.84 ITGB3 (0.34) OPRK1OPRM1ITGB3ITGA2BKCNH2
SCHEMBL6487237 0.83 ITGB3 (0.37) OPRK1OPRM1ITGB3ITGA2BKCNH2
Hydrochloric Acid SCHEMBL6485317 0.82 ITGB3 (0.38) OPRK1ITGB3ITGA2BKCNH2F2
SCHEMBL6475692 0.82 ITGB3 (0.36) ITGB3ITGA2BF2
SCHEMBL6485408 0.81 ITGB3 (0.34) OPRK1OPRM1ITGB3ITGA2BKCNH2
SCHEMBL6484317 0.81 ITGB3 (0.37) OPRK1OPRM1ITGB3ITGA2BKCNH2
SCHEMBL6475187 0.80 F2 (0.33) OPRK1ITGB3ITGA2BKCNH2F2
SCHEMBL6482270 0.80 ITGB3 (0.35) OPRK1ITGB3ITGA2BKCNH2F2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1996025426-A1 NOVEL DIPEPTIDE AMIDINES AS THROMBIN INHIBITORS BASF AKTIENGESELLSCHAFT (DE) 1996-08-22 WO disclosed