Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.50 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
| ▸ | RELA | Q04206 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.44 |
| ▸ | LTC4S | Q16873 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.43 |
| ▸ | ABL1 | P00519 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4213158 | 0.87 | HRH4 (0.55) | HRH4HRH3EGLN1RAB9AMAPT | |
| SCHEMBL2086752 | 0.86 | HRH4 (0.54) | HRH4HRH3EGLN1RAB9AMAPT | |
| SCHEMBL2086534 | 0.82 | HRH4 (0.50) | HRH4HRH3EGLN1RAB9AKDM4E | |
| SCHEMBL4211423 | 0.82 | RAB9A (0.53) | HRH4HRH3EGLN1RAB9AKDM4E | |
| SCHEMBL4213470 | 0.81 | EGLN1 (0.49) | EGLN1 | |
| SCHEMBL4220034 | 0.81 | HRH4 (0.48) | HRH4HRH3EGLN1RAB9AMAPT | |
| SCHEMBL4243985 | 0.77 | HRH4 (0.48) | HRH4HRH3EGLN1RAB9AKDM4E | |
| SCHEMBL8182174 | 0.77 | HRH4 (0.66) | HRH4HRH3MAPTKDM4EALDH1A1 | |
| SCHEMBL2087963 | 0.76 | HRH4 (0.50) | HPGDHRH4HRH3EGLN1RAB9A | |
| SCHEMBL4242240 | 0.76 | EGLN1 (0.53) | HPGDHRH4HRH3EGLN1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996025414-A1 | IMIDAZO[1,2-A]PYRIDINES FOR THE TREATMENT OF CNS AND CARDIAC DISEASES | PHARMACIA & UPJOHN COMPANY (US) | 1996-08-22 | — | — | WO | disclosed |