Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 6/20 | 0.40 |
| ▸ | MGAM | O43451 | 2/20 | 0.40 |
| ▸ | SI | P14410 | 2/20 | 0.40 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.40 |
| ▸ | IGF1R | P08069 | 1/20 | 0.39 |
| ▸ | PTP4A3 | O75365 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | DVL1 | O14640 | 1/20 | 0.38 |
| ▸ | PIM1 | P11309 | 2/20 | 0.37 |
| ▸ | PIM3 | Q86V86 | 2/20 | 0.37 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.37 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.37 |
| ▸ | MEN1 | O00255 | 6/20 | 0.37 |
| ▸ | MAPT | P10636 | 6/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.37 |
| ▸ | POLB | P06746 | 3/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8991940 | 1.00 | GAA (0.40) | GAAMGAMSIMGAM2IGF1R | |
| SCHEMBL8537293 | 0.88 | GAA (0.38) | GAAMGAMSIMGAM2IGF1R | |
| SCHEMBL8535804 | 0.88 | GAA (0.38) | GAAMGAMSIMGAM2IGF1R | |
| SCHEMBL8537292 | 0.88 | GAA (0.38) | GAAMGAMSIMGAM2IGF1R | |
| SCHEMBL8310599 | 0.83 | MAPT (0.56) | GAAPTP4A3DVL1KMT2AMEN1 | |
| SCHEMBL8310604 | 0.83 | MAPT (0.56) | GAAPTP4A3DVL1KMT2AMEN1 | |
| SCHEMBL8933557 | 0.82 | IGF1R (0.44) | GAAMGAMSIMGAM2IGF1R | |
| SCHEMBL8933553 | 0.82 | IGF1R (0.44) | GAAMGAMSIMGAM2IGF1R | |
| SCHEMBL8307819 | 0.80 | DYRK1A (0.61) | GAAMGAMSIMGAM2IGF1R | |
| SCHEMBL8307815 | 0.80 | DYRK1A (0.61) | GAAMGAMSIMGAM2IGF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996022772-A1 | METHOD FOR TREATING MULTIPLE SCLEROSIS | ELI LILLY AND COMPANY (US) | 1996-08-01 | — | — | WO | disclosed |
| EP-0722729-A2 | Aryl-substituted rhodanines for treating multiple sclerosis | ELI LILLY AND COMPANY (US) | 1996-07-24 | — | — | EP | disclosed |