Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8933532 | 0.83 | LTA4H (0.50) | LTA4HTAAR1TDP1L3MBTL1NPC1 | |
| SCHEMBL8933602 | 0.80 | LTA4H (0.50) | LTA4HTAAR1TDP1L3MBTL1NPC1 | |
| SCHEMBL2355634 | 0.76 | LTA4H (0.75) | LTA4HTAAR1TDP1L3MBTL1NPC1 | |
| SCHEMBL28615289 | 0.75 | TDP1 (0.54) | LTA4HTDP1L3MBTL1NPC1RAB9A | |
| SCHEMBL971238 | 0.72 | LTA4H (0.53) | LTA4HL3MBTL1NPC1RAB9ASIGMAR1 | |
| SCHEMBL5632470 | 0.72 | LTA4H (0.69) | LTA4HTAAR1TDP1L3MBTL1NPC1 | |
| SCHEMBL9054554 | 0.72 | F2RL1 (0.53) | TAAR1CALM1MAOB | |
| SCHEMBL834551 | 0.71 | TAAR1 (0.73) | LTA4HTAAR1SIGMAR1CALM1MAOB | |
| Anisole SCHEMBL17629450 | 0.71 | LTA4H (0.61) | LTA4HTAAR1TDP1L3MBTL1NPC1 | |
| SCHEMBL12040566 | 0.71 | TDP1 (0.75) | LTA4HTAAR1TDP1L3MBTL1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996024601-A1 | COMPLEXES, PROCESSES FOR THEIR PREPARATION AND THEIR USE | UNIVERSITY COLLEGE DUBLIN (IE) | 1996-08-15 | — | — | WO | claimed |
| WO-1996024601-A1 | COMPLEXES, PROCESSES FOR THEIR PREPARATION AND THEIR USE | UNIVERSITY COLLEGE DUBLIN (IE) | 1996-08-15 | — | — | WO | disclosed |